Water-dispersible tryptophan-protected gold nanoparticles prepared by the spontaneous reduction of aqueous chloroaurate ions by the amino acid

P. R. Selvakannan, Saikat Mandal, Sumant Phadtare, Anand Gole, Renu Pasricha, S. D. Adyanthaya, Murali Sastry

Research output: Contribution to journalArticle

Abstract

The synthesis of water-dispersible amino-acid-protected gold nanoparticles by the spontaneous reduction of aqueous chloroaurate ions by tryptophan is described. Water-dispersible gold nanoparticles may also be obtained by the sequential synthesis of the gold nanoparticles by borohydride reduction of chloroauric acid followed by capping with tryptophan. Comparison of the proton NMR spectroscopic signatures from the tryptophan-protected gold nanoparticles obtained by the two processes indicated that the indole group in tryptophan is responsible for reduction of the aqueous chloroaurate ions. The reduction of the metal ions is accompanied by oxidative polymerization of the indole group of the tryptophan molecules and, consequently, some degree of cross-linking of the gold nanoparticles.

Original languageEnglish (US)
Pages (from-to)97-102
Number of pages6
JournalJournal of Colloid and Interface Science
Volume269
Issue number1
DOIs
StatePublished - Jan 1 2004

Fingerprint

Tryptophan
Gold
Amino acids
Ions
Nanoparticles
Amino Acids
Water
Borohydrides
Metal ions
Protons
Polymerization
Nuclear magnetic resonance
Molecules
Acids
indole

Keywords

  • Amino acids
  • Electrostatic stabilization
  • Nanoparticles
  • NMR
  • Surface modification

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Surfaces, Coatings and Films
  • Colloid and Surface Chemistry

Cite this

Water-dispersible tryptophan-protected gold nanoparticles prepared by the spontaneous reduction of aqueous chloroaurate ions by the amino acid. / Selvakannan, P. R.; Mandal, Saikat; Phadtare, Sumant; Gole, Anand; Pasricha, Renu; Adyanthaya, S. D.; Sastry, Murali.

In: Journal of Colloid and Interface Science, Vol. 269, No. 1, 01.01.2004, p. 97-102.

Research output: Contribution to journalArticle

Selvakannan, P. R. ; Mandal, Saikat ; Phadtare, Sumant ; Gole, Anand ; Pasricha, Renu ; Adyanthaya, S. D. ; Sastry, Murali. / Water-dispersible tryptophan-protected gold nanoparticles prepared by the spontaneous reduction of aqueous chloroaurate ions by the amino acid. In: Journal of Colloid and Interface Science. 2004 ; Vol. 269, No. 1. pp. 97-102.
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AU - Gole, Anand

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AB - The synthesis of water-dispersible amino-acid-protected gold nanoparticles by the spontaneous reduction of aqueous chloroaurate ions by tryptophan is described. Water-dispersible gold nanoparticles may also be obtained by the sequential synthesis of the gold nanoparticles by borohydride reduction of chloroauric acid followed by capping with tryptophan. Comparison of the proton NMR spectroscopic signatures from the tryptophan-protected gold nanoparticles obtained by the two processes indicated that the indole group in tryptophan is responsible for reduction of the aqueous chloroaurate ions. The reduction of the metal ions is accompanied by oxidative polymerization of the indole group of the tryptophan molecules and, consequently, some degree of cross-linking of the gold nanoparticles.

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