Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body

Marie Christine Clugnet, Joseph Ledoux, Shaun F. Morrison

Research output: Contribution to journalArticle

Abstract

Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.

Original languageEnglish (US)
Pages (from-to)1055-1061
Number of pages7
JournalJournal of Neuroscience
Volume10
Issue number4
StatePublished - 1990

Fingerprint

Geniculate Bodies
Putamen
Amygdala
Electric Stimulation
Reaction Time
Chloral Hydrate
Thalamus
Acoustics
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body. / Clugnet, Marie Christine; Ledoux, Joseph; Morrison, Shaun F.

In: Journal of Neuroscience, Vol. 10, No. 4, 1990, p. 1055-1061.

Research output: Contribution to journalArticle

@article{25615e517a004a2da7bfc80471f13e59,
title = "Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body",
abstract = "Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.",
author = "Clugnet, {Marie Christine} and Joseph Ledoux and Morrison, {Shaun F.}",
year = "1990",
language = "English (US)",
volume = "10",
pages = "1055--1061",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "4",

}

TY - JOUR

T1 - Unit responses evoked in the amygdala and striatum by electrical stimulation of the medial geniculate body

AU - Clugnet, Marie Christine

AU - Ledoux, Joseph

AU - Morrison, Shaun F.

PY - 1990

Y1 - 1990

N2 - Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.

AB - Unit activity was recorded from cells and cell clusters in the amygdala and striatum in response to electrical stimulation of the medial geniculate body (MGB) in rats anesthetized with chloral hydrate. Responses were mostly excitatory and were evoked against a relatively silent background (i.e., the units seldom fired between stimuli). The shortest latency responses were recorded in the caudate putamen (CPU), lateral amygdaloid nucleus (AL), and amygdalostriatal transition area (AST). Longer latency responses were obtained from neurons in the basolateral (ABL), basomedial (ABM), and central (ACE) nuclei of the amygdala. Moreover, while responses were evoked in AL, AST, and CPU with 300-500 MA stimuli delivered once every 10 sec, more intense and higher-frequency stimuli were required to obtain responses in ABL, ABM, and ACE. These findings are consistent with anatomical tracing studies showing that AL, AST, and CPU receive direct projections from the MGB and related acoustic processing areas of the thalamus but that ACE, ABL, and ABM do not.

UR - http://www.scopus.com/inward/record.url?scp=0025411360&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025411360&partnerID=8YFLogxK

M3 - Article

VL - 10

SP - 1055

EP - 1061

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 4

ER -