Ultrahigh-resolution spectral domain optical coherence tomography imaging of the lamina cribrosa

Larry Kagemann, Hiroshi Ishikawa, Gadi WollStein, Peter M. Brennen, Kelly A. Townsend, Michelle L. Gabriele, Joel S. Schuman

    Research output: Contribution to journalArticle

    Abstract

    Study of the structure of the lamina cribrosa is critical in glaucoma research. The purpose of this study is to determine the optimal spectral domain optical coherence tomography imaging protocol for the digital isolation and display of the lamina cribrosa. Three-dimensional datasets centered on the lamina cribrosa were obtained with 200 × 200 to 512 × 512 A-scan densities. The effect of scan density and c-mode slab thickness was subjectively compared. Increasing slab thickness reduced the sharpness of visible prelamina and lamina cribrosa structures. In retrolamina structures, thin slabs provided good visualization, but increased slab size increased the visibility of deeper structures. Scan times as short as 2.3 seconds (256 × 256 A-scans) degraded visualization of the shape of the optic nerve head. The optical scan protocol for lamina cribrosa imaging appears to be a 3 × 3 mm 200 × 200 A-scan volume with the lamina cribrosa positioned near direct current.

    Original languageEnglish (US)
    Pages (from-to)S126-S131
    JournalOphthalmic Surgery Lasers and Imaging
    Volume39
    Issue number4 SUPPL.
    StatePublished - Jul 1 2008

    ASJC Scopus subject areas

    • Surgery
    • Ophthalmology

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  • Cite this

    Kagemann, L., Ishikawa, H., WollStein, G., Brennen, P. M., Townsend, K. A., Gabriele, M. L., & Schuman, J. S. (2008). Ultrahigh-resolution spectral domain optical coherence tomography imaging of the lamina cribrosa. Ophthalmic Surgery Lasers and Imaging, 39(4 SUPPL.), S126-S131.