Two functional effects of decreased conductance EPSP's: Synaptic augmentation and increased electrotonic coupling

Thomas J. Carew, Eric R. Kandel

Research output: Contribution to journalArticle


Three electronically coupled motor neurons, which mediate inking behavior in Aplysia californica, receive both increased and decreased conductance excitatory postsynaptic potentials (EPSP's). The increased conductance EPSP's reduce electrical coupling among the cells, whereas the decreased conductance EPSP's increase electrical coupling. The decreased conductance EPSP's also augment the action of a previously ineffective sensory input and this augmentation is enhanced by the increase in electrical coupling. Both effects combine to trigger a stereotypic behavioral response.

Original languageEnglish (US)
Pages (from-to)150-153
Number of pages4
Issue number4235
StatePublished - Jan 1 1976


ASJC Scopus subject areas

  • General

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