Two dimensional PNA/DNA arrays

Estimating the helicity of unusual nucleic acid polymers

Philip S. Lukeman, Alexander C. Mittal, Nadrian Seeman

Research output: Contribution to journalArticle

Abstract

We extend the generality of nucleic acid-based structural nanotechnology by incorporating non-natural nucleic acids into a DNA double crossover (DX) molecule; visualizing two-dimensional arrays of these DX molecules by Atomic Force Microscopy (AFM) enables us to measure the helical repeat of any heteroduplex sequence capable of forming the outer arms of a DX.

Original languageEnglish (US)
Pages (from-to)1694-1695
Number of pages2
JournalChemical Communications
Volume10
Issue number15
StatePublished - Aug 7 2004

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Nucleic acids
Nucleic Acids
Polymers
DNA
Molecules
Nanotechnology
Atomic force microscopy

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Two dimensional PNA/DNA arrays : Estimating the helicity of unusual nucleic acid polymers. / Lukeman, Philip S.; Mittal, Alexander C.; Seeman, Nadrian.

In: Chemical Communications, Vol. 10, No. 15, 07.08.2004, p. 1694-1695.

Research output: Contribution to journalArticle

Lukeman, Philip S. ; Mittal, Alexander C. ; Seeman, Nadrian. / Two dimensional PNA/DNA arrays : Estimating the helicity of unusual nucleic acid polymers. In: Chemical Communications. 2004 ; Vol. 10, No. 15. pp. 1694-1695.
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