Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015

findings from the Global Burden of Disease 2015 study

GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

Research output: Contribution to journalArticle

Abstract

Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

Original languageEnglish (US)
Pages (from-to)123-136
Number of pages14
JournalInternational Journal of Public Health
Volume63
DOIs
StatePublished - May 1 2018

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Mediterranean Region
Acquired Immunodeficiency Syndrome
HIV
Morbidity
Mortality
Life Expectancy
Population
Global Burden of Disease
Weights and Measures

Keywords

  • Burden of disease
  • Eastern Mediterranean Region
  • HIV
  • HIV mortality

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this

Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015 : findings from the Global Burden of Disease 2015 study. / GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators.

In: International Journal of Public Health, Vol. 63, 01.05.2018, p. 123-136.

Research output: Contribution to journalArticle

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title = "Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015: findings from the Global Burden of Disease 2015 study",
abstract = "Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43{\%} increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.",
keywords = "Burden of disease, Eastern Mediterranean Region, HIV, HIV mortality",
author = "{GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators} and {El Bcheraoui}, Charbel and Haidong Wang and Raghid Charara and Ibrahim Khalil and Maziar Moradi-Lakeh and Ashkan Afshin and Michael Collison and Farah Daoud and Adrienne Chew and Krohn, {Kristopher J.} and Austin Carter and Foreman, {Kyle J.} and Fei He and Kassebaum, {Nicholas J.} and Michael Kutz and Mojde Mirarefin and Grant Nguyen and Naris Silpakit and Amber Sligar and Abajobir, {Amanuel A.} and Abate, {Kalkidan H.} and Abbas, {Kaja M.} and Foad Abd-Allah and Abera, {Semaw F.} and Kelemework Adane and Arnav Agarwal and Aliasghar Ahmadkiadaliri and Alireza Ahmadi and Ahmed, {Muktar B.} and {Al Lami}, {Faris H.} and Khurshid Alam and Deena Alasfoor and Reza Alizadeh-Navaei and Fatma Al-Maskari and Rajaa Al-Raddadi and Altirkawi, {Khalid A.} and Nelson Alvis-Guzman and Walid Ammar and Nahla Anber and Antonio, {Carl Abelardo T.} and Palwasha Anwari and Hamid Asayesh and Asghar, {Rana J.} and Atey, {Tesfay Mehari} and Avokpaho, {Euripide F.G.A.} and Tadesse Awokeayele and Peter Azzopardi and Umar Bacha and Aleksandra Barac and {Des Jarlais}, Don",
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T1 - Trends in HIV/AIDS morbidity and mortality in Eastern Mediterranean countries, 1990–2015

T2 - findings from the Global Burden of Disease 2015 study

AU - GBD 2015 Eastern Mediterranean Region HIV/AIDS Collaborators

AU - El Bcheraoui, Charbel

AU - Wang, Haidong

AU - Charara, Raghid

AU - Khalil, Ibrahim

AU - Moradi-Lakeh, Maziar

AU - Afshin, Ashkan

AU - Collison, Michael

AU - Daoud, Farah

AU - Chew, Adrienne

AU - Krohn, Kristopher J.

AU - Carter, Austin

AU - Foreman, Kyle J.

AU - He, Fei

AU - Kassebaum, Nicholas J.

AU - Kutz, Michael

AU - Mirarefin, Mojde

AU - Nguyen, Grant

AU - Silpakit, Naris

AU - Sligar, Amber

AU - Abajobir, Amanuel A.

AU - Abate, Kalkidan H.

AU - Abbas, Kaja M.

AU - Abd-Allah, Foad

AU - Abera, Semaw F.

AU - Adane, Kelemework

AU - Agarwal, Arnav

AU - Ahmadkiadaliri, Aliasghar

AU - Ahmadi, Alireza

AU - Ahmed, Muktar B.

AU - Al Lami, Faris H.

AU - Alam, Khurshid

AU - Alasfoor, Deena

AU - Alizadeh-Navaei, Reza

AU - Al-Maskari, Fatma

AU - Al-Raddadi, Rajaa

AU - Altirkawi, Khalid A.

AU - Alvis-Guzman, Nelson

AU - Ammar, Walid

AU - Anber, Nahla

AU - Antonio, Carl Abelardo T.

AU - Anwari, Palwasha

AU - Asayesh, Hamid

AU - Asghar, Rana J.

AU - Atey, Tesfay Mehari

AU - Avokpaho, Euripide F.G.A.

AU - Awokeayele, Tadesse

AU - Azzopardi, Peter

AU - Bacha, Umar

AU - Barac, Aleksandra

AU - Des Jarlais, Don

PY - 2018/5/1

Y1 - 2018/5/1

N2 - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

AB - Objectives: We used the results of the Global Burden of Disease 2015 study to estimate trends of HIV/AIDS burden in Eastern Mediterranean Region (EMR) countries between 1990 and 2015. Methods: Tailored estimation methods were used to produce final estimates of mortality. Years of life lost (YLLs) were calculated by multiplying the mortality rate by population by age-specific life expectancy. Years lived with disability (YLDs) were computed as the prevalence of a sequela multiplied by its disability weight. Results: In 2015, the rate of HIV/AIDS deaths in the EMR was 1.8 (1.4–2.5) per 100,000 population, a 43% increase from 1990 (0.3; 0.2–0.8). Consequently, the rate of YLLs due to HIV/AIDS increased from 15.3 (7.6–36.2) per 100,000 in 1990 to 81.9 (65.3–114.4) in 2015. The rate of YLDs increased from 1.3 (0.6–3.1) in 1990 to 4.4 (2.7–6.6) in 2015. Conclusions: HIV/AIDS morbidity and mortality increased in the EMR since 1990. To reverse this trend and achieve epidemic control, EMR countries should strengthen HIV surveillance, and scale up HIV antiretroviral therapy and comprehensive prevention services.

KW - Burden of disease

KW - Eastern Mediterranean Region

KW - HIV

KW - HIV mortality

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U2 - 10.1007/s00038-017-1023-0

DO - 10.1007/s00038-017-1023-0

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VL - 63

SP - 123

EP - 136

JO - International Journal of Public Health

JF - International Journal of Public Health

SN - 1661-8556

ER -