Translating basic behavioral and social science research to clinical application

the EVOLVE mixed methods approach.

Janey C. Peterson, Susan Czajkowski, Mary E. Charlson, Alissa R. Link, Martin T. Wells, Alice M. Isen, Carol A. Mancuso, John P. Allegrante, Carla Boutin-Foster, Gbenga Ogedegbe, Jared B. Jobe

Research output: Contribution to journalArticle

Abstract

To describe a mixed-methods approach to develop and test a basic behavioral science-informed intervention to motivate behavior change in 3 high-risk clinical populations. Our theoretically derived intervention comprised a combination of positive affect and self-affirmation (PA/SA), which we applied to 3 clinical chronic disease populations. We employed a sequential mixed methods model (EVOLVE) to design and test the PA/SA intervention in order to increase physical activity in people with coronary artery disease (post-percutaneous coronary intervention [PCI]) or asthma (ASM) and to improve medication adherence in African Americans with hypertension (HTN). In an initial qualitative phase, we explored participant values and beliefs. We next pilot tested and refined the intervention and then conducted 3 randomized controlled trials with parallel study design. Participants were randomized to combined PA/SA versus an informational control and were followed bimonthly for 12 months, assessing for health behaviors and interval medical events. Over 4.5 years, we enrolled 1,056 participants. Changes were sequentially made to the intervention during the qualitative and pilot phases. The 3 randomized controlled trials enrolled 242 participants who had undergone PCI, 258 with ASM, and 256 with HTN (n = 756). Overall, 45.1% of PA/SA participants versus 33.6% of informational control participants achieved successful behavior change (p = .001). In multivariate analysis, PA/SA intervention remained a significant predictor of achieving behavior change (p <.002, odds ratio = 1.66), 95% CI [1.22, 2.27], controlling for baseline negative affect, comorbidity, gender, race/ethnicity, medical events, smoking, and age. The EVOLVE method is a means by which basic behavioral science research can be translated into efficacious interventions for chronic disease populations.

Original languageEnglish (US)
Pages (from-to)217-230
Number of pages14
JournalJournal of Consulting and Clinical Psychology
Volume81
Issue number2
StatePublished - Apr 2013

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Behavioral Sciences
Social Sciences
Research
Percutaneous Coronary Intervention
Chronic Disease
Asthma
Randomized Controlled Trials
Population
Hypertension
Behavioral Research
Medication Adherence
Health Behavior
African Americans
Mixed Methods
Behavioral Science
Translating
Comorbidity
Coronary Artery Disease
Multivariate Analysis
Smoking

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Psychology
  • Arts and Humanities (miscellaneous)
  • Medicine(all)

Cite this

Peterson, J. C., Czajkowski, S., Charlson, M. E., Link, A. R., Wells, M. T., Isen, A. M., ... Jobe, J. B. (2013). Translating basic behavioral and social science research to clinical application: the EVOLVE mixed methods approach. Journal of Consulting and Clinical Psychology, 81(2), 217-230.

Translating basic behavioral and social science research to clinical application : the EVOLVE mixed methods approach. / Peterson, Janey C.; Czajkowski, Susan; Charlson, Mary E.; Link, Alissa R.; Wells, Martin T.; Isen, Alice M.; Mancuso, Carol A.; Allegrante, John P.; Boutin-Foster, Carla; Ogedegbe, Gbenga; Jobe, Jared B.

In: Journal of Consulting and Clinical Psychology, Vol. 81, No. 2, 04.2013, p. 217-230.

Research output: Contribution to journalArticle

Peterson, JC, Czajkowski, S, Charlson, ME, Link, AR, Wells, MT, Isen, AM, Mancuso, CA, Allegrante, JP, Boutin-Foster, C, Ogedegbe, G & Jobe, JB 2013, 'Translating basic behavioral and social science research to clinical application: the EVOLVE mixed methods approach.', Journal of Consulting and Clinical Psychology, vol. 81, no. 2, pp. 217-230.
Peterson, Janey C. ; Czajkowski, Susan ; Charlson, Mary E. ; Link, Alissa R. ; Wells, Martin T. ; Isen, Alice M. ; Mancuso, Carol A. ; Allegrante, John P. ; Boutin-Foster, Carla ; Ogedegbe, Gbenga ; Jobe, Jared B. / Translating basic behavioral and social science research to clinical application : the EVOLVE mixed methods approach. In: Journal of Consulting and Clinical Psychology. 2013 ; Vol. 81, No. 2. pp. 217-230.
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