Total synthesis of (±)-rhazinal using novel palladium-catalyzed cyclizations

Alfred L. Bowie, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

A concise synthesis of (±)-rhazinal that hinges on novel oxidative Heck cyclizations and palladium- catalyzed direct couplings is described. An X-ray structure of N-MOM-rhazinal, which provides insight into the conformation of the strained 9-membered lactam ring, is described.

Original languageEnglish (US)
Pages (from-to)1581-1586
Number of pages6
JournalJournal of Organic Chemistry
Volume74
Issue number4
DOIs
StatePublished - Feb 20 2009

ASJC Scopus subject areas

  • Organic Chemistry

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