The what, where and how of delay activity

Kartik K. Sreenivasan, Mark D’Esposito

Research output: Contribution to journalReview article

Abstract

Working memory is characterized by neural activity that persists during the retention interval of delay tasks. Despite the ubiquity of this delay activity across tasks, species and experimental techniques, our understanding of this phenomenon remains incomplete. Although initially there was a narrow focus on sustained activation in a small number of brain regions, methodological and analytical advances have allowed researchers to uncover previously unobserved forms of delay activity various parts of the brain. In light of these new findings, this Review reconsiders what delay activity is, where in the brain it is found, what roles it serves and how it may be generated.

Original languageEnglish (US)
Pages (from-to)466-481
Number of pages16
JournalNature Reviews Neuroscience
Volume20
Issue number8
DOIs
StatePublished - Aug 1 2019

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ASJC Scopus subject areas

  • Neuroscience(all)

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