The UAE healthy future study

a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals

Abdishakur Abdulle, Abdullah Alnaeemi, Abdullah Aljunaibi, Abdulrahman Al Ali, Khaled Al Saedi, Eiman Al Zaabi, Naima Oumeziane, Marina Al Bastaki, Mohammed Al-Houqani, Fatma Al Maskari, Ayesha Al Dhaheri, Syed M. Shah, Tom Loney, Mohamed El-Sadig, Abderrahim Oulhaj, Leila Abdel Wareth, Wael Al Mahmeed, Habiba Alsafar, Benjamin Hirsch, Fatme Al Anouti & 18 others Jamila Yaaqoub, Claire K. Inman, Aisha Al Hamiz, Ayesha Al Hosani, Muna Haji, Teeb Alsharid, Thekra Al Zaabi, Fatima Al Maisary, Divya Galani, Tim Sprosen, Omar El Shahawy, Jiyoung Ahn, Tomas Kirchhoff, Ravichandran Ramasamy, Ann Marie Schmidt, Richard Hayes, Scott Sherman, Raghib Ali

    Research output: Contribution to journalArticle

    Abstract

    BACKGROUND: The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses.

    METHODS: Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at -80 °C for future analyses.

    RESULTS: Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively.

    CONCLUSIONS: The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.

    Original languageEnglish (US)
    Number of pages1
    JournalBMC Public Health
    Volume18
    Issue number1
    DOIs
    StatePublished - Jan 5 2018

    Fingerprint

    United Arab Emirates
    Cohort Studies
    Prospective Studies
    Mouthwashes
    Feasibility Studies
    Hematology
    Informed Consent
    Cardiovascular Diseases
    Obesity
    Urine
    DNA
    Serum

    Keywords

    • Adult
    • Chronic disease
    • Cohort studies
    • Pilot projects
    • Prospective studies
    • Public health
    • United Arab Emirates

    ASJC Scopus subject areas

    • Public Health, Environmental and Occupational Health

    Cite this

    Abdulle, A., Alnaeemi, A., Aljunaibi, A., Al Ali, A., Al Saedi, K., Al Zaabi, E., ... Ali, R. (2018). The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals. BMC Public Health, 18(1). https://doi.org/10.1186/s12889-017-5012-2

    The UAE healthy future study : a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals. / Abdulle, Abdishakur; Alnaeemi, Abdullah; Aljunaibi, Abdullah; Al Ali, Abdulrahman; Al Saedi, Khaled; Al Zaabi, Eiman; Oumeziane, Naima; Al Bastaki, Marina; Al-Houqani, Mohammed; Al Maskari, Fatma; Al Dhaheri, Ayesha; Shah, Syed M.; Loney, Tom; El-Sadig, Mohamed; Oulhaj, Abderrahim; Wareth, Leila Abdel; Al Mahmeed, Wael; Alsafar, Habiba; Hirsch, Benjamin; Al Anouti, Fatme; Yaaqoub, Jamila; Inman, Claire K.; Al Hamiz, Aisha; Al Hosani, Ayesha; Haji, Muna; Alsharid, Teeb; Al Zaabi, Thekra; Al Maisary, Fatima; Galani, Divya; Sprosen, Tim; El Shahawy, Omar; Ahn, Jiyoung; Kirchhoff, Tomas; Ramasamy, Ravichandran; Schmidt, Ann Marie; Hayes, Richard; Sherman, Scott; Ali, Raghib.

    In: BMC Public Health, Vol. 18, No. 1, 05.01.2018.

    Research output: Contribution to journalArticle

    Abdulle, A, Alnaeemi, A, Aljunaibi, A, Al Ali, A, Al Saedi, K, Al Zaabi, E, Oumeziane, N, Al Bastaki, M, Al-Houqani, M, Al Maskari, F, Al Dhaheri, A, Shah, SM, Loney, T, El-Sadig, M, Oulhaj, A, Wareth, LA, Al Mahmeed, W, Alsafar, H, Hirsch, B, Al Anouti, F, Yaaqoub, J, Inman, CK, Al Hamiz, A, Al Hosani, A, Haji, M, Alsharid, T, Al Zaabi, T, Al Maisary, F, Galani, D, Sprosen, T, El Shahawy, O, Ahn, J, Kirchhoff, T, Ramasamy, R, Schmidt, AM, Hayes, R, Sherman, S & Ali, R 2018, 'The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals', BMC Public Health, vol. 18, no. 1. https://doi.org/10.1186/s12889-017-5012-2
    Abdulle, Abdishakur ; Alnaeemi, Abdullah ; Aljunaibi, Abdullah ; Al Ali, Abdulrahman ; Al Saedi, Khaled ; Al Zaabi, Eiman ; Oumeziane, Naima ; Al Bastaki, Marina ; Al-Houqani, Mohammed ; Al Maskari, Fatma ; Al Dhaheri, Ayesha ; Shah, Syed M. ; Loney, Tom ; El-Sadig, Mohamed ; Oulhaj, Abderrahim ; Wareth, Leila Abdel ; Al Mahmeed, Wael ; Alsafar, Habiba ; Hirsch, Benjamin ; Al Anouti, Fatme ; Yaaqoub, Jamila ; Inman, Claire K. ; Al Hamiz, Aisha ; Al Hosani, Ayesha ; Haji, Muna ; Alsharid, Teeb ; Al Zaabi, Thekra ; Al Maisary, Fatima ; Galani, Divya ; Sprosen, Tim ; El Shahawy, Omar ; Ahn, Jiyoung ; Kirchhoff, Tomas ; Ramasamy, Ravichandran ; Schmidt, Ann Marie ; Hayes, Richard ; Sherman, Scott ; Ali, Raghib. / The UAE healthy future study : a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals. In: BMC Public Health. 2018 ; Vol. 18, No. 1.
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    title = "The UAE healthy future study: a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals",
    abstract = "BACKGROUND: The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses.METHODS: Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at -80 °C for future analyses.RESULTS: Overall, 517 Emirati men and women agreed to participate (68{\%} response rate). Of the total participants, 495 (95.0{\%}), 430 (82.2{\%}), and 492 (94.4{\%}), completed the questionnaire, physical measurements, and provided biological samples, respectively.CONCLUSIONS: The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.",
    keywords = "Adult, Chronic disease, Cohort studies, Pilot projects, Prospective studies, Public health, United Arab Emirates",
    author = "Abdishakur Abdulle and Abdullah Alnaeemi and Abdullah Aljunaibi and {Al Ali}, Abdulrahman and {Al Saedi}, Khaled and {Al Zaabi}, Eiman and Naima Oumeziane and {Al Bastaki}, Marina and Mohammed Al-Houqani and {Al Maskari}, Fatma and {Al Dhaheri}, Ayesha and Shah, {Syed M.} and Tom Loney and Mohamed El-Sadig and Abderrahim Oulhaj and Wareth, {Leila Abdel} and {Al Mahmeed}, Wael and Habiba Alsafar and Benjamin Hirsch and {Al Anouti}, Fatme and Jamila Yaaqoub and Inman, {Claire K.} and {Al Hamiz}, Aisha and {Al Hosani}, Ayesha and Muna Haji and Teeb Alsharid and {Al Zaabi}, Thekra and {Al Maisary}, Fatima and Divya Galani and Tim Sprosen and {El Shahawy}, Omar and Jiyoung Ahn and Tomas Kirchhoff and Ravichandran Ramasamy and Schmidt, {Ann Marie} and Richard Hayes and Scott Sherman and Raghib Ali",
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    month = "1",
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    doi = "10.1186/s12889-017-5012-2",
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    TY - JOUR

    T1 - The UAE healthy future study

    T2 - a pilot for a prospective cohort study of 20,000 United Arab Emirates nationals

    AU - Abdulle, Abdishakur

    AU - Alnaeemi, Abdullah

    AU - Aljunaibi, Abdullah

    AU - Al Ali, Abdulrahman

    AU - Al Saedi, Khaled

    AU - Al Zaabi, Eiman

    AU - Oumeziane, Naima

    AU - Al Bastaki, Marina

    AU - Al-Houqani, Mohammed

    AU - Al Maskari, Fatma

    AU - Al Dhaheri, Ayesha

    AU - Shah, Syed M.

    AU - Loney, Tom

    AU - El-Sadig, Mohamed

    AU - Oulhaj, Abderrahim

    AU - Wareth, Leila Abdel

    AU - Al Mahmeed, Wael

    AU - Alsafar, Habiba

    AU - Hirsch, Benjamin

    AU - Al Anouti, Fatme

    AU - Yaaqoub, Jamila

    AU - Inman, Claire K.

    AU - Al Hamiz, Aisha

    AU - Al Hosani, Ayesha

    AU - Haji, Muna

    AU - Alsharid, Teeb

    AU - Al Zaabi, Thekra

    AU - Al Maisary, Fatima

    AU - Galani, Divya

    AU - Sprosen, Tim

    AU - El Shahawy, Omar

    AU - Ahn, Jiyoung

    AU - Kirchhoff, Tomas

    AU - Ramasamy, Ravichandran

    AU - Schmidt, Ann Marie

    AU - Hayes, Richard

    AU - Sherman, Scott

    AU - Ali, Raghib

    PY - 2018/1/5

    Y1 - 2018/1/5

    N2 - BACKGROUND: The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses.METHODS: Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at -80 °C for future analyses.RESULTS: Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively.CONCLUSIONS: The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.

    AB - BACKGROUND: The United Arab Emirates (UAE) is faced with a rapidly increasing burden of non-communicable diseases including obesity, diabetes, and cardiovascular disease. The UAE Healthy Future study is a prospective cohort designed to identify associations between risk factors and these diseases amongst Emiratis. The study will enroll 20,000 UAE nationals aged ≥18 years. Environmental and genetic risk factors will be characterized and participants will be followed for future disease events. As this was the first time a prospective cohort study was being planned in the UAE, a pilot study was conducted in 2015 with the primary aim of establishing the feasibility of conducting the study. Other objectives were to evaluate the implementation of the main study protocols, and to build adequate capacity to conduct advanced clinical laboratory analyses.METHODS: Seven hundred sixty nine UAE nationals aged ≥18 years were invited to participate voluntarily in the pilot study. Participants signed an informed consent, completed a detailed questionnaire, provided random blood, urine, and mouthwash samples and were assessed for a series of clinical measures. All specimens were transported to the New York University Abu Dhabi laboratories where samples were processed and analyzed for routine chemistry and hematology. Plasma, serum, and a small whole blood sample for DNA extraction were aliquoted and stored at -80 °C for future analyses.RESULTS: Overall, 517 Emirati men and women agreed to participate (68% response rate). Of the total participants, 495 (95.0%), 430 (82.2%), and 492 (94.4%), completed the questionnaire, physical measurements, and provided biological samples, respectively.CONCLUSIONS: The pilot study demonstrated the feasibility of recruitment and completion of the study protocols for the first large-scale cohort study designed to identify emerging risk factors for the major non-communicable diseases in the region.

    KW - Adult

    KW - Chronic disease

    KW - Cohort studies

    KW - Pilot projects

    KW - Prospective studies

    KW - Public health

    KW - United Arab Emirates

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    DO - 10.1186/s12889-017-5012-2

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    VL - 18

    JO - BMC Public Health

    JF - BMC Public Health

    SN - 1471-2458

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