The social realities of adherence to protease inhibitor regimens: Substance use, health care and psychological states

Perry N. Halkitis, Alexandra H. Kutnick, Simon Slater

Research output: Contribution to journalArticle

Abstract

Adherence to HIV antiretroviral treatments is impacted by a variety of factors nested within the realities of people's lives. To understand this phenomenon, we undertook an investigation to assess HIV medication adherence in a community-based sample of 300 HIV seropositive men-who-have-sex-with-men (MSM). Using multiple measurement strategies (self-report, electronic monitoring, calendar-based assessments) we assessed factors related to medication adherence. Our findings indicate that adherence to protease inhibitor regimens are highly variable and are related to contextual, intrapersonal and behavioral factors, including access to health care, the use of specific recreational substances, self-efficacy toward adherence and avoidant coping strategies. These results suggest that a complex interaction between intrapsychic and socio-cultural realities may help to explain adherence to HIV treatment medications.

Original languageEnglish (US)
Pages (from-to)545-558
Number of pages14
JournalJournal of Health Psychology
Volume10
Issue number4
DOIs
StatePublished - Jul 1 2005

Keywords

  • Adherence
  • Drug use
  • Gay/bisexual
  • HAART
  • HIV
  • MSM

ASJC Scopus subject areas

  • Applied Psychology

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