The potential protective effects of taurine on coronary heart disease

Oktawia P. Wójcik, Karen L. Koenig, Anne Zeleniuch-Jacquotte, Max Costa, Yu Chen

Research output: Contribution to journalReview article

Abstract

In humans, taurine (2-aminoethanesulfonic acid) is mainly obtained from diet. Despite the fact that the health effects of taurine are largely unknown, taurine has become a popular supplement and ingredient in energy drinks in recent years. Evidence from mechanistic and animal studies has shown that the main biological actions of taurine include its ability to conjugate bile acids, regulate blood pressure (BP), and act as a potent antioxidant and anti-inflammatory agent. These actions suggest that high levels of taurine may be protective against coronary heart disease (CHD). However, data from epidemiologic and intervention studies in humans are limited. We review what is known about taurine's metabolism, its transportation in the body, its food sources, and evidence of its effect on cardiovascular health from in vitro, animal, and epidemiologic studies. We also discuss shortcomings of the human studies that need to be addressed in the future. The identification of taurine as a preventive factor for CHD may be of great public health importance.

Original languageEnglish (US)
Pages (from-to)19-25
Number of pages7
JournalAtherosclerosis
Volume208
Issue number1
DOIs
StatePublished - Jan 2010

Fingerprint

Taurine
Coronary Disease
Epidemiologic Studies
Energy Drinks
Health
Bile Acids and Salts
Anti-Inflammatory Agents
Public Health
Antioxidants
Diet
Blood Pressure
Food
Acids

Keywords

  • Antioxidant
  • Blood pressure
  • Cholesterol
  • Coronary heart disease
  • Taurine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

The potential protective effects of taurine on coronary heart disease. / Wójcik, Oktawia P.; Koenig, Karen L.; Zeleniuch-Jacquotte, Anne; Costa, Max; Chen, Yu.

In: Atherosclerosis, Vol. 208, No. 1, 01.2010, p. 19-25.

Research output: Contribution to journalReview article

Wójcik, OP, Koenig, KL, Zeleniuch-Jacquotte, A, Costa, M & Chen, Y 2010, 'The potential protective effects of taurine on coronary heart disease', Atherosclerosis, vol. 208, no. 1, pp. 19-25. https://doi.org/10.1016/j.atherosclerosis.2009.06.002
Wójcik, Oktawia P. ; Koenig, Karen L. ; Zeleniuch-Jacquotte, Anne ; Costa, Max ; Chen, Yu. / The potential protective effects of taurine on coronary heart disease. In: Atherosclerosis. 2010 ; Vol. 208, No. 1. pp. 19-25.
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