The origin of the S (slow) potential in the mammalian Lateral Geniculate Nucleus

E. Kaplan, Robert Shapley

Research output: Contribution to journalArticle

Abstract

While recording extracellularly from single neurons in the Lateral Geniculate Nucleus (LGN) of cats and monkeys, one often observes, in addition to action potentials, smaller and slower potentials which have been called 'S Potentials' (Bishop et al. 1962). Injection of the sodium channel blocker tetrodotoxin (TTX) into the eye of the cat causes spontaneous and light evoked S potentials to disappear. However, electrical stimulation of ganglion cells axons at the optic chiasm still elicits S potentials. Previous studies have shown that retinal ganglion cell impulses elicit S potentials. Our results prove that ganglion cell impulses are the ONLY source of these potentials; therefore, one can use them as a measure of ganglion cell input to the LGN.

Original languageEnglish (US)
Pages (from-to)111-116
Number of pages6
JournalExperimental Brain Research
Volume55
Issue number1
DOIs
StatePublished - May 1984

Fingerprint

Geniculate Bodies
Ganglia
Cats
Sodium Channel Blockers
Optic Chiasm
Retinal Ganglion Cells
Tetrodotoxin
Evoked Potentials
Electric Stimulation
Action Potentials
Haplorhini
Axons
Neurons
Light
Injections

Keywords

  • Lateral geniculate nucleus
  • S potential
  • Thalamus

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The origin of the S (slow) potential in the mammalian Lateral Geniculate Nucleus. / Kaplan, E.; Shapley, Robert.

In: Experimental Brain Research, Vol. 55, No. 1, 05.1984, p. 111-116.

Research output: Contribution to journalArticle

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