The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study

Abdulla Shehab, Bayan Al-Dabbagh, Khalid Alhabib, Alawi Alsheikh-Ali, Wael Almahmeed, Kadhim Sulaiman, Ahmed Al-Motarreb, Jassim Al Suwaidi, Ahmad Hersi, Hussam Alfaleh, Nidal Asaad, Shukri Alsaif, Haitham Amin, Muath Alanbaei, Nicolaas Nagelkerke, Abdishakur Abdulle

Research output: Contribution to journalArticle

Abstract

We investigated the association between in-hospital and peri-hospital mortality and body mass index (BMI)/waist circumference (WC) in a prospective acute coronary syndrome (ACS) registry in the Arabian Gulf. No significant associations with in-hospital mortality were found. Normal BMI had highest peri-hospital mortality, notably those with high WC. In logistic regression of mortality on obesity measures and potential confounders, the effects of obesity measures were no longer significant. In-hospital death increased by 5% with age and decreased by 42% in males. Mortality increased 3.7-fold with ST-elevation myocardial infarction (STEMI) and 3.0-fold with heart failure (HF) but decreased by 33% with dyslipidemia. Peri-hospital death increased by 4% with age and decreased by 30% in males. Mortality increased 2.8-fold with STEMI and 2.4-fold with HF. In- and peri-hospital mortality in ACS is significantly associated with age, gender, STEMI, HF, and dyslipidemia but not obesity measures.

Original languageEnglish (US)
Pages (from-to)585-589
Number of pages5
JournalAngiology
Volume65
Issue number7
DOIs
StatePublished - Jan 1 2014

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Acute Coronary Syndrome
Hospital Mortality
Obesity
Heart Failure
Waist Circumference
Dyslipidemias
Mortality
Body Mass Index
Registries
Logistic Models
ST Elevation Myocardial Infarction

Keywords

  • ACS
  • Arabian Gulf
  • mortality
  • obesity

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

Cite this

Shehab, A., Al-Dabbagh, B., Alhabib, K., Alsheikh-Ali, A., Almahmeed, W., Sulaiman, K., ... Abdulle, A. (2014). The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study. Angiology, 65(7), 585-589. https://doi.org/10.1177/0003319713497087

The obesity paradox in patients with acute coronary syndrome : Results from the gulf RACE-2 study. / Shehab, Abdulla; Al-Dabbagh, Bayan; Alhabib, Khalid; Alsheikh-Ali, Alawi; Almahmeed, Wael; Sulaiman, Kadhim; Al-Motarreb, Ahmed; Suwaidi, Jassim Al; Hersi, Ahmad; Alfaleh, Hussam; Asaad, Nidal; Alsaif, Shukri; Amin, Haitham; Alanbaei, Muath; Nagelkerke, Nicolaas; Abdulle, Abdishakur.

In: Angiology, Vol. 65, No. 7, 01.01.2014, p. 585-589.

Research output: Contribution to journalArticle

Shehab, A, Al-Dabbagh, B, Alhabib, K, Alsheikh-Ali, A, Almahmeed, W, Sulaiman, K, Al-Motarreb, A, Suwaidi, JA, Hersi, A, Alfaleh, H, Asaad, N, Alsaif, S, Amin, H, Alanbaei, M, Nagelkerke, N & Abdulle, A 2014, 'The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study', Angiology, vol. 65, no. 7, pp. 585-589. https://doi.org/10.1177/0003319713497087
Shehab A, Al-Dabbagh B, Alhabib K, Alsheikh-Ali A, Almahmeed W, Sulaiman K et al. The obesity paradox in patients with acute coronary syndrome: Results from the gulf RACE-2 study. Angiology. 2014 Jan 1;65(7):585-589. https://doi.org/10.1177/0003319713497087
Shehab, Abdulla ; Al-Dabbagh, Bayan ; Alhabib, Khalid ; Alsheikh-Ali, Alawi ; Almahmeed, Wael ; Sulaiman, Kadhim ; Al-Motarreb, Ahmed ; Suwaidi, Jassim Al ; Hersi, Ahmad ; Alfaleh, Hussam ; Asaad, Nidal ; Alsaif, Shukri ; Amin, Haitham ; Alanbaei, Muath ; Nagelkerke, Nicolaas ; Abdulle, Abdishakur. / The obesity paradox in patients with acute coronary syndrome : Results from the gulf RACE-2 study. In: Angiology. 2014 ; Vol. 65, No. 7. pp. 585-589.
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