The laminar distributions and postnatal development of neurotransmitter and neuromodulator receptors in cat visual cortex

C. Shaw, M. Wilkinson, M. Cynader, M. C. Needler, Chiye Aoki, S. E. Hall

Research output: Contribution to journalArticle

Abstract

We review efforts to further understand the development and nature of sensory processing mechanisms in the cat visual cortex. In vitro autoradiographic and homogenate assay techniques have been employed to determine the laminar distribution and characteristics of various neurotransmitter and neuromodulator receptor populations during postnatal development. Each receptor population shows a distinct laminar-specific pattern of binding, which, in most cases, is age-dependent. Changes in receptor number and affinity are also observed during postnatal development. These findings indicate that major alterations in the basic chemical circuitry of cat visual cortex are a normal feature of postnatal maturation and may play a role in plasticity mechanisms.

Original languageEnglish (US)
Pages (from-to)661-671
Number of pages11
JournalBrain Research Bulletin
Volume16
Issue number5
DOIs
StatePublished - 1986

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Neurotransmitter Receptor
Visual Cortex
Cats
Population
In Vitro Techniques

Keywords

  • Cats
  • Laminar distribution
  • Neuromodulator receptors
  • Neurotransmitter receptors
  • Postnatal development
  • Visual cortex

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

The laminar distributions and postnatal development of neurotransmitter and neuromodulator receptors in cat visual cortex. / Shaw, C.; Wilkinson, M.; Cynader, M.; Needler, M. C.; Aoki, Chiye; Hall, S. E.

In: Brain Research Bulletin, Vol. 16, No. 5, 1986, p. 661-671.

Research output: Contribution to journalArticle

Shaw, C. ; Wilkinson, M. ; Cynader, M. ; Needler, M. C. ; Aoki, Chiye ; Hall, S. E. / The laminar distributions and postnatal development of neurotransmitter and neuromodulator receptors in cat visual cortex. In: Brain Research Bulletin. 1986 ; Vol. 16, No. 5. pp. 661-671.
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