The Interaction of Risk Network Structures and Virus Natural History in the Non-spreading of HIV Among People Who Inject Drugs in the Early Stages of the Epidemic

Kirk Dombrowski, Bilal Khan, Patrick Habecker, Holly Hagan, Samuel R. Friedman, Mohamed Saad

Research output: Contribution to journalArticle

Abstract

This article explores how social network dynamics may have reduced the spread of HIV-1 infection among people who inject drugs during the early years of the epidemic. Stochastic, discrete event, agent-based simulations are used to test whether a “firewall effect” can arise out of self-organizing processes at the actor level, and whether such an effect can account for stable HIV prevalence rates below population saturation. Repeated simulation experiments show that, in the presence of recurring, acute, and highly infectious outbreaks, micro-network structures combine with the HIV virus’s natural history to reduce the spread of the disease. These results indicate that network factors likely played a significant role in the prevention of HIV infection within injection risk networks during periods of peak prevalence. They also suggest that social forces that disturb network connections may diminish the natural firewall effect and result in higher rates of HIV.

Original languageEnglish (US)
Pages (from-to)1-12
Number of pages12
JournalAIDS and Behavior
DOIs
StateAccepted/In press - Oct 3 2016

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Viral Structures
Natural History
HIV
HIV Infections
Pharmaceutical Preparations
Social Support
Disease Outbreaks
HIV-1
Injections
Population

Keywords

  • Firewall effect
  • PWID
  • Risk networks
  • Simulation

ASJC Scopus subject areas

  • Social Psychology
  • Public Health, Environmental and Occupational Health
  • Infectious Diseases

Cite this

The Interaction of Risk Network Structures and Virus Natural History in the Non-spreading of HIV Among People Who Inject Drugs in the Early Stages of the Epidemic. / Dombrowski, Kirk; Khan, Bilal; Habecker, Patrick; Hagan, Holly; Friedman, Samuel R.; Saad, Mohamed.

In: AIDS and Behavior, 03.10.2016, p. 1-12.

Research output: Contribution to journalArticle

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