The evolution of molecular genetic pathways and networks

Jennifer M. Cork, Michael D. Purugganan

Research output: Contribution to journalArticle

Abstract

There is growing interest in the evolutionary dynamics of molecular genetic pathways and networks, and the extent to which the molecular evolution of a gene depends on its position within a pathway or network, as well as over-all network topology. Investigations on the relationships between network organization, topological architecture and evolutionary dynamics provide intriguing hints as to how networks evolve. Recent studies also suggest that genetic pathway and network structures may influence the action of evolutionary forces, and may play a role in maintaining phenotypic robustness in organisms.

Original languageEnglish (US)
Pages (from-to)479-484
Number of pages6
JournalBioEssays
Volume26
Issue number5
DOIs
StatePublished - May 2004

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Molecular Evolution
molecular genetics
Molecular Biology
topology
Genes
Topology
organisms
genes

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Biochemistry
  • Cell Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Agricultural and Biological Sciences (miscellaneous)
  • Plant Science

Cite this

The evolution of molecular genetic pathways and networks. / Cork, Jennifer M.; Purugganan, Michael D.

In: BioEssays, Vol. 26, No. 5, 05.2004, p. 479-484.

Research output: Contribution to journalArticle

Cork, Jennifer M. ; Purugganan, Michael D. / The evolution of molecular genetic pathways and networks. In: BioEssays. 2004 ; Vol. 26, No. 5. pp. 479-484.
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