The effect of implant diameter on osseointegration utilizing simplified drilling protocols

Ryo Jimbo, Malvin N. Janal, Charles Marin, Gabriela Giro, Nick Tovar, Paulo Coelho

Research output: Contribution to journalArticle

Abstract

Objectives: To observe and to compare histologically and histomorphometrically, the combined effect of drilling sequence and implant diameter in vivo. Material and Methods: A total of 72 alumina-blasted and acid-etched Ti-6Al-4V implants with three different diameters (3.75, 4.2, and 5 mm, n = 24 for each group) were placed in the right and left tibiae of 12 beagle dogs. Within the same diameter group, half of the implants were inserted after a simplified drilling procedure (pilot drill + final diameter drill) on one tibia and the other half were placed using the conventional drilling procedure on the other tibia. After 1 week, half of the animals (n = 6) were sacrificed, and the other half was sacrificed after 5 weeks (n = 6). The retrieved bone-implant samples were subjected to non-decalcified histologic sectioning, and the bone-to-implant contact (BIC) and the bone area fraction occupancy (BAFO) were analyzed. Primary statistical analysis used a mixed model analysis of variance with significance level set at P < 0.05. Results: Histologic observation showed that at 1 week, immature woven bone formed in vicinity of the implant, whereas at 5 weeks, the woven bone was replaced by lamellar bone, which formed in proximity with the implant.Histomorphometrically, the simplified technique was associated with significantly greater BIC and BAFO after 1 week. Differences between techniques were not longer apparent after 5 weeks, but BAFO was inversely and significantly associated with implant diameter at that time. Conclusions: The simplified technique did not impair either early or late bone formation for any tested implant diameter; however, wider diameters were associated with less bone formation at longer healing times for both techniques.

Original languageEnglish (US)
Pages (from-to)1295-1300
Number of pages6
JournalClinical Oral Implants Research
Volume25
Issue number11
DOIs
StatePublished - 2014

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Osseointegration
Bone and Bones
Tibia
Mandrillus
Osteogenesis
Aluminum Oxide
Analysis of Variance
Observation
Dogs
Acids

Keywords

  • Animal experiments
  • Bone implant interactions
  • Surgical techniques

ASJC Scopus subject areas

  • Oral Surgery

Cite this

The effect of implant diameter on osseointegration utilizing simplified drilling protocols. / Jimbo, Ryo; Janal, Malvin N.; Marin, Charles; Giro, Gabriela; Tovar, Nick; Coelho, Paulo.

In: Clinical Oral Implants Research, Vol. 25, No. 11, 2014, p. 1295-1300.

Research output: Contribution to journalArticle

Jimbo, Ryo ; Janal, Malvin N. ; Marin, Charles ; Giro, Gabriela ; Tovar, Nick ; Coelho, Paulo. / The effect of implant diameter on osseointegration utilizing simplified drilling protocols. In: Clinical Oral Implants Research. 2014 ; Vol. 25, No. 11. pp. 1295-1300.
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