The B-alkyl suzuki-miyaura cross-coupling reaction

Development, mechanistic study, and applications in natural product synthesis

Sherry R. Chemler, Dirk Trauner, Samuel J. Danishefsky

Research output: Contribution to journalReview article

Abstract

The development of new reactions that facilitate the creative and efficient synthesis of molecular structures with desirable properties continues to fascinate chemists. The test of a significant contribution is its acceptance over time by the scientific community. The B-alkyl Suzuki-Miyaura crosscoupling reaction appears to be one such reaction. Since its disclosure by Suzuki and Miyaura in 1986, this reaction has been an attractive solution to challenging synthetic problems.

Original languageEnglish (US)
Pages (from-to)4544-4568
Number of pages25
JournalAngewandte Chemie - International Edition
Volume40
Issue number24
DOIs
StatePublished - Dec 17 2001

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Biological Products
Molecular structure

Keywords

  • Boranes
  • C-C coupling
  • Cross-coupling
  • Suzuki-Miyaura coupling
  • Synthetic methods

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Cite this

The B-alkyl suzuki-miyaura cross-coupling reaction : Development, mechanistic study, and applications in natural product synthesis. / Chemler, Sherry R.; Trauner, Dirk; Danishefsky, Samuel J.

In: Angewandte Chemie - International Edition, Vol. 40, No. 24, 17.12.2001, p. 4544-4568.

Research output: Contribution to journalReview article

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