Temporal summation and refractoriness in hypothalamic reward neurons as measured by self-stimulation behavior

Nicole Schupf Smith, Edgar E. Coons

Research output: Contribution to journalArticle

Abstract

A neurophysiological technique of double-pulse stimulation has been applied to freely moving rats with chronic indwelling electrodes in the hypothalamic reward area. Self-stimulation thresholds, measured as a function of the interpulse interval, generated curves with time constants characteristic of refractory periods and temporal synoptic summation. The results indicate a way of studying central neuronal processes for which the overt behavior of the animal is the dependent variable.

Original languageEnglish (US)
Pages (from-to)782-785
Number of pages4
JournalScience
Volume169
Issue number3947
StatePublished - 1970

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Self Stimulation
Reward
Neurons
Animal Behavior
Electrodes

ASJC Scopus subject areas

  • General

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Temporal summation and refractoriness in hypothalamic reward neurons as measured by self-stimulation behavior. / Smith, Nicole Schupf; Coons, Edgar E.

In: Science, Vol. 169, No. 3947, 1970, p. 782-785.

Research output: Contribution to journalArticle

Smith, Nicole Schupf ; Coons, Edgar E. / Temporal summation and refractoriness in hypothalamic reward neurons as measured by self-stimulation behavior. In: Science. 1970 ; Vol. 169, No. 3947. pp. 782-785.
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