Synthesis of sheet-coil-helix and coil-sheet-helix triblock copolymers by combining ROMP with palladium-mediated isocyanide polymerization

Scott K. Pomarico, Diane S. Lye, Elizabeth Elacqua, Marcus Weck

Research output: Contribution to journalArticle

Abstract

We report a synthetic route to construct architecturally well-defined triblock copolymers, in particular copolymers featuring secondary structures that form sheet-coil-helix and coil-sheet-helix motifs, through a macroinitiation strategy that combines sequential ring-opening metathesis polymerization (ROMP) with palladium-mediated isocyanide polymerization. Throughout the triblock copolymer fabrication, the individual blocks retained their secondary structures as evidenced by circular dicroism (CD) and fluorescence spectroscopies. Our strategy introduces a facile way to create complex ABC triblock copolymers that contain architecturally-diverse backbones, whilst retaining the ability to control sequence: sheet-coil-helix or coil-sheet-helix.

Original languageEnglish (US)
Pages (from-to)5655-5659
Number of pages5
JournalPolymer Chemistry
Volume9
Issue number48
DOIs
StatePublished - Dec 28 2018

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Ring opening polymerization
Palladium
Cyanides
Polymerization
Block copolymers
Fluorescence Spectrometry
Fluorescence spectroscopy
Copolymers
Fabrication

ASJC Scopus subject areas

  • Bioengineering
  • Biochemistry
  • Polymers and Plastics
  • Organic Chemistry

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Synthesis of sheet-coil-helix and coil-sheet-helix triblock copolymers by combining ROMP with palladium-mediated isocyanide polymerization. / Pomarico, Scott K.; Lye, Diane S.; Elacqua, Elizabeth; Weck, Marcus.

In: Polymer Chemistry, Vol. 9, No. 48, 28.12.2018, p. 5655-5659.

Research output: Contribution to journalArticle

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