Synthesis of artificial receptors as potential candidates for recognition and binding of pterin analogs

M. V. Papadopoulou, S. Goswami, Andrew Hamilton

Research output: Contribution to journalArticle

Abstract

Open chain podands 2a-c and macrocycles 2d-e have been synthesized as potential candidates for 4-aminopterin recognition and binding, featuring H-bonding characteristics and 'stacking interaction' 2e. Preliminary binding studies between 6, 7, and 8 (simpler analogs of the above 2a-e) as 'hosts' and appropriate 'guests', showed that carbamates 2a and 2e are the most promising receptors for 4-aminopterin binding.

Original languageEnglish (US)
Pages (from-to)675-681
Number of pages7
JournalJournal of Heterocyclic Chemistry
Volume32
Issue number2
StatePublished - 1995

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Aminopterin
Artificial Receptors
Pterins
Carbamates

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis of artificial receptors as potential candidates for recognition and binding of pterin analogs. / Papadopoulou, M. V.; Goswami, S.; Hamilton, Andrew.

In: Journal of Heterocyclic Chemistry, Vol. 32, No. 2, 1995, p. 675-681.

Research output: Contribution to journalArticle

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