Synthesis of a stable gold hydrosol by the reduction of chloroaurate ions by the amino acid, aspartic acid

Saikat Mandal, P. R. Selvakannan, Sumant Phadtare, Renu Pasricha, Murali Sastry

Research output: Contribution to journalArticle

Abstract

Development of reliable protocols for the synthesis of nanoparticles of well-defined sizes and good monodispersity is an important aspect of nanotechnology. In this paper, we present details of the synthesis of gold nanoparticles of good monodispersity by the reduction of aqueous chloroaurate ions by the amino acid, aspartic acid. The colloidal gold solution thus formed is extremely stable in time, indicating electrostatic stabilization via nanoparticle surface-bound amino acid molecules. This observation has been used to modulate the size of the gold nanoparticles in solution by varying the molar ratio of chloroaurate ions to aspartic acid in the reaction medium. Characterization of the aspartic acid-reduced gold nanoparticles was carried out by UV-visible spectroscopy, thermogravimetric analysis and transmission electron microscopy. The use of amino acids in the synthesis and stabilization of gold nanoparticle in water has important implications in the development of new protocols for generation of bioconjugate materials.

Original languageEnglish (US)
Pages (from-to)513-520
Number of pages8
JournalProceedings of the Indian Academy of Sciences: Chemical Sciences
Volume114
Issue number5
DOIs
StatePublished - Jan 1 2002

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Aspartic Acid
Gold
Ions
Nanoparticles
Amino Acids
Stabilization
Gold Colloid
Nanotechnology
Thermogravimetric analysis
Electrostatics
Spectroscopy
Transmission electron microscopy
Molecules
Water

Keywords

  • Bioconjugates
  • Gold nanoparticles
  • Reduction by amino acids
  • Surface modification

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Synthesis of a stable gold hydrosol by the reduction of chloroaurate ions by the amino acid, aspartic acid. / Mandal, Saikat; Selvakannan, P. R.; Phadtare, Sumant; Pasricha, Renu; Sastry, Murali.

In: Proceedings of the Indian Academy of Sciences: Chemical Sciences, Vol. 114, No. 5, 01.01.2002, p. 513-520.

Research output: Contribution to journalArticle

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