Switching Gears: Translational Mastery of Transcription during Memory Formation

Charles A. Hoeffer, Eric Klann

Research output: Contribution to journalArticle

Abstract

A critical molecular requirement underlying many forms of long-lasting synaptic plasticity and memory is the de novo synthesis of mRNAs and proteins. In a recent paper in Cell, Costa-Mattioli et al. present data from a pharmacogenetic study that places a key regulatory event in the "neural decision" to undergo these persistent neuronal changes under translational control mediated by eIF2α.

Original languageEnglish (US)
Pages (from-to)186-189
Number of pages4
JournalNeuron
Volume54
Issue number2
DOIs
StatePublished - Apr 19 2007

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Neuronal Plasticity
Messenger RNA
Proteins
Pharmacogenomic Testing

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Switching Gears : Translational Mastery of Transcription during Memory Formation. / Hoeffer, Charles A.; Klann, Eric.

In: Neuron, Vol. 54, No. 2, 19.04.2007, p. 186-189.

Research output: Contribution to journalArticle

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