Specifying the contributions of the human amygdala to emotional memory: A case study

Elizabeth A. Phelps, Kevin S. Labar, Adam K. Anderson, Kevin J. O'Connor, Robert K. Fulbright, Dennis D. Spencer

Research output: Contribution to journalArticle

Abstract

We examined emotional memory in patient SP, a 54-year-old woman with bilateral damage to the amygdala. Consistent with previous case studies, SP showed deficits on tests of fear conditioning and recognition memory for arousing stimuli. SP's performance on several emotional episodic memory tasks was examined. We found that bilateral damage to the amygdala only leads to deficits on a subset of emotional episodic memory tasks. Specifically, the amygdala does not seem to be involved when episodic memory performance benefits from the valence of the stimuli. However, when episodic memory benefits from arousal, damage to the amygdala leads to a deficit in performance. Based on our results, we postulate that the amygdala is not involved when emotion enhances episodic memory primarily by contributing an organizing principle such as a schema or category. We expect the effects of amygdala damage to be limited to memory tasks affected by the neuromodulatory changes that occur with arousal. The effects of arousal on episodic memory would be most apparent in the rate of forgetting for arousing stimuli, the recall of arousing stimuli that have a weak central theme, and the recognition of details or events associated with arousing stimuli.

Original languageEnglish (US)
Pages (from-to)527-540
Number of pages14
JournalNeurocase
Volume4
Issue number6
DOIs
StatePublished - 1998

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Episodic Memory
Amygdala
Arousal
Pentosan Sulfuric Polyester
Fear
Emotion
Emotions
Stimulus
Damage

Keywords

  • Amygdala
  • Arousal
  • Emotion
  • Emotional memory
  • Episodic memory
  • Fear conditioning
  • Medial temporal lobe epilepsy
  • Memory
  • Valence

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology
  • Psychiatry and Mental health
  • Psychology(all)

Cite this

Phelps, E. A., Labar, K. S., Anderson, A. K., O'Connor, K. J., Fulbright, R. K., & Spencer, D. D. (1998). Specifying the contributions of the human amygdala to emotional memory: A case study. Neurocase, 4(6), 527-540. https://doi.org/10.1093/neucas/4.6.527

Specifying the contributions of the human amygdala to emotional memory : A case study. / Phelps, Elizabeth A.; Labar, Kevin S.; Anderson, Adam K.; O'Connor, Kevin J.; Fulbright, Robert K.; Spencer, Dennis D.

In: Neurocase, Vol. 4, No. 6, 1998, p. 527-540.

Research output: Contribution to journalArticle

Phelps, EA, Labar, KS, Anderson, AK, O'Connor, KJ, Fulbright, RK & Spencer, DD 1998, 'Specifying the contributions of the human amygdala to emotional memory: A case study', Neurocase, vol. 4, no. 6, pp. 527-540. https://doi.org/10.1093/neucas/4.6.527
Phelps, Elizabeth A. ; Labar, Kevin S. ; Anderson, Adam K. ; O'Connor, Kevin J. ; Fulbright, Robert K. ; Spencer, Dennis D. / Specifying the contributions of the human amygdala to emotional memory : A case study. In: Neurocase. 1998 ; Vol. 4, No. 6. pp. 527-540.
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