Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats

Benjamin B. Scott, Christine Constantinople, Jeffrey C. Erlich, David W. Tank, Carlos D. Brody

Research output: Contribution to journalArticle

Abstract

Decision-making behavior is often characterized by substantial variability, but its source remains unclear. We developed a visual accumulation of evidence task designed to quantify sources of noise and to be performed during voluntary head restraint, enabling cellular resolution imaging in future studies. Rats accumulated discrete numbers of flashes presented to the left and right visual hemifields and indicated the side that had the greater number of flashes. Using a signal-detection theory-based model, we found that the standard deviation in their internal estimate of flash number scaled linearly with the number of flashes. This indicates a major source of noise that, surprisingly, is not consistent with the widely used ’drift-diffusion modeling’ (DDM) approach but is instead closely related to proposed models of numerical cognition and counting. We speculate that this form of noise could be important in accumulation of evidence tasks generally.

Original languageEnglish (US)
Article numbere11308
JournaleLife
Volume4
Issue numberDECEMBER2015
DOIs
StatePublished - Dec 17 2015

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Noise
Rats
Head
Signal detection
Decision making
Imaging techniques
Cognition
Decision Making
Psychological Signal Detection

ASJC Scopus subject areas

  • Neuroscience(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Immunology and Microbiology(all)

Cite this

Scott, B. B., Constantinople, C., Erlich, J. C., Tank, D. W., & Brody, C. D. (2015). Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats. eLife, 4(DECEMBER2015), [e11308]. https://doi.org/10.7554/eLife.11308

Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats. / Scott, Benjamin B.; Constantinople, Christine; Erlich, Jeffrey C.; Tank, David W.; Brody, Carlos D.

In: eLife, Vol. 4, No. DECEMBER2015, e11308, 17.12.2015.

Research output: Contribution to journalArticle

Scott, BB, Constantinople, C, Erlich, JC, Tank, DW & Brody, CD 2015, 'Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats', eLife, vol. 4, no. DECEMBER2015, e11308. https://doi.org/10.7554/eLife.11308
Scott BB, Constantinople C, Erlich JC, Tank DW, Brody CD. Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats. eLife. 2015 Dec 17;4(DECEMBER2015). e11308. https://doi.org/10.7554/eLife.11308
Scott, Benjamin B. ; Constantinople, Christine ; Erlich, Jeffrey C. ; Tank, David W. ; Brody, Carlos D. / Sources of noise during accumulation of evidence in unrestrained and voluntarily head-restrained rats. In: eLife. 2015 ; Vol. 4, No. DECEMBER2015.
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