Solid phase synthesis of hydrogen bond surrogate derived α-helices: Resolving the case of a difficult amide coupling

Anupam Patgiri, Michael R. Witten, Paramjit S. Arora

Research output: Contribution to journalArticle

Abstract

Solid phase synthesis of HBS helices involving the Fukuyama-Mitsunobu reaction and triphosgene coupling is described.

Original languageEnglish (US)
Pages (from-to)1773-1776
Number of pages4
JournalOrganic and Biomolecular Chemistry
Volume8
Issue number8
DOIs
StatePublished - Apr 7 2010

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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