Sleep duration and the risk of diabetes mellitus: Epidemiologic evidence and pathophysiologic insights

Ferdinand Zizi, Girardin Jean-Louis, Clinton D. Brown, Gbenga Ogedegbe, Carla Boutin-Foster, Samy I. McFarlane

Research output: Contribution to journalReview article

Abstract

Evidence from well-defined cohort studies has shown that short sleep, through sleep fragmentation caused by obstructive sleep apnea (OSA) or behavioral sleep curtailment because of lifestyle choices, is associated with increased incidence of diabetes. In this report, we review epidemiologic and clinical data suggesting that OSA is involved in the pathogenesis of altered glucose metabolism. Evidence suggesting increased risk of developing diabetes resulting from curtailed sleep duration is also considered. Proposed mechanisms explaining associations between short sleep and diabetes are examined and clinical management of OSA among patients with diabetes is discussed.

Original languageEnglish (US)
Pages (from-to)43-47
Number of pages5
JournalCurrent Diabetes Reports
Volume10
Issue number1
DOIs
StatePublished - Feb 1 2010

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Keywords

  • Diabetes
  • Glucose levels
  • Sleep apnea
  • Sleep duration

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism

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