Sensory convergence solves a motion ambiguity problem

Aasef G. Shaikh, Andrea M. Green, Fatema F. Ghasia, Shawn D. Newlands, J. David Dickman, Dora Angelaki

Research output: Contribution to journalArticle

Abstract

Our inner ear is equipped with a set of linear accelerometers, the otolith organs, that sense the inertial accelerations experienced during self-motion [1, 2]. However, as Einstein pointed out nearly a century ago [3], this signal would by itself be insufficient to detect our real movement, because gravity, another form of linear acceleration, and self-motion are sensed identically by otolith afferents. To deal with this ambiguity, it was proposed that neural populations in the pons and midline cerebellum compute an independent, internal estimate of gravity using signals arising from the vestibular rotation sensors, the semicircular canals [4-7]. This hypothesis, regarding a causal relationship between firing rates and postulated sensory contributions to inertial motion estimation, has been directly tested here by recording neural activities before and after inactivation of the semicircular canals. We show that, unlike cells in normal animals, the gravity component of neural responses was nearly absent in canal-inactivated animals. We conclude that, through integration of temporally matched, multimodal information, neurons derive the mathematical signals predicted by the equations describing the physics of the outside world.

Original languageEnglish (US)
Pages (from-to)1657-1662
Number of pages6
JournalCurrent Biology
Volume15
Issue number18
DOIs
StatePublished - Sep 20 2005

Fingerprint

Gravitation
Canals
gravity
Otolithic Membrane
Semicircular Canals
otoliths
Animals
Sense Organs
Pons
sense organs
Physics
Motion estimation
cerebellum
Inner Ear
physics
Accelerometers
Cerebellum
Neurons
ears
animals

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)

Cite this

Shaikh, A. G., Green, A. M., Ghasia, F. F., Newlands, S. D., Dickman, J. D., & Angelaki, D. (2005). Sensory convergence solves a motion ambiguity problem. Current Biology, 15(18), 1657-1662. https://doi.org/10.1016/j.cub.2005.08.009

Sensory convergence solves a motion ambiguity problem. / Shaikh, Aasef G.; Green, Andrea M.; Ghasia, Fatema F.; Newlands, Shawn D.; Dickman, J. David; Angelaki, Dora.

In: Current Biology, Vol. 15, No. 18, 20.09.2005, p. 1657-1662.

Research output: Contribution to journalArticle

Shaikh, AG, Green, AM, Ghasia, FF, Newlands, SD, Dickman, JD & Angelaki, D 2005, 'Sensory convergence solves a motion ambiguity problem', Current Biology, vol. 15, no. 18, pp. 1657-1662. https://doi.org/10.1016/j.cub.2005.08.009
Shaikh AG, Green AM, Ghasia FF, Newlands SD, Dickman JD, Angelaki D. Sensory convergence solves a motion ambiguity problem. Current Biology. 2005 Sep 20;15(18):1657-1662. https://doi.org/10.1016/j.cub.2005.08.009
Shaikh, Aasef G. ; Green, Andrea M. ; Ghasia, Fatema F. ; Newlands, Shawn D. ; Dickman, J. David ; Angelaki, Dora. / Sensory convergence solves a motion ambiguity problem. In: Current Biology. 2005 ; Vol. 15, No. 18. pp. 1657-1662.
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