Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain

William Maixner, Roger Fillingim, Donna Booker, Asgeir Sigurdsson

Research output: Contribution to journalArticle

Abstract

Temporomandibular disorders (TMD) represent a group of chronic painful conditions involving the muscles of mastication and the temporomandibular joint. We determined whether patients with painful TMD are more sensitive to noxious stimuli than age-matched control subjects. Fifty-two TMD patients (16 with muscle pain and 36 with combined muscle and joint pain) and 23 age-matched and gender-matched volunteers participated. Forearm thermal pain threshold and tolerance values were determined. A submaximal effort tourniquet procedure was used to evoke ischemic muscle pain. Relative to control subjects, TMD patients had significantly lower thermal pain threshold, ischemic pain threshold, and ischemic pain tolerance values; and thermal pain tolerance values also tended to be lower. Pain sensitivity did not differ between the two groups of TMD patients. Furthermore, the submaximal effort tourniquet procedure, which is capable of altering acute orofacial pain (Sigurdsson and Maixner, 1994) did not produce a consistent reduction in orofacial pain associated with TMD. We concluded that TMD patients are more sensitive to noxious stimuli than pain-free controls. These findings provide additional evidence that TMD is a psychophysiological disorder of the central nervous system which modulates emotional, physiological and neuroendocrine responses to emotional and physical stressors.

Original languageEnglish (US)
Pages (from-to)341-351
Number of pages11
JournalPain
Volume63
Issue number3
DOIs
StatePublished - 1995

Fingerprint

Temporomandibular Joint Disorders
Pain
Pain Threshold
Myalgia
Tourniquets
Facial Pain
Hot Temperature
Psychophysiologic Disorders
Mastication
Temporomandibular Joint
Arthralgia
Acute Pain
Forearm
Volunteers
Central Nervous System
Muscles

Keywords

  • Myofascial pain
  • Pain sensitivity
  • Temporomandibular disorder
  • Temporomandibular joint disorder

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine
  • Clinical Neurology
  • Neurology
  • Pharmacology
  • Psychiatry and Mental health
  • Neuroscience(all)
  • Clinical Psychology

Cite this

Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain. / Maixner, William; Fillingim, Roger; Booker, Donna; Sigurdsson, Asgeir.

In: Pain, Vol. 63, No. 3, 1995, p. 341-351.

Research output: Contribution to journalArticle

Maixner, William ; Fillingim, Roger ; Booker, Donna ; Sigurdsson, Asgeir. / Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain. In: Pain. 1995 ; Vol. 63, No. 3. pp. 341-351.
@article{085a31c736f34d5f96deaeb8691420d8,
title = "Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain",
abstract = "Temporomandibular disorders (TMD) represent a group of chronic painful conditions involving the muscles of mastication and the temporomandibular joint. We determined whether patients with painful TMD are more sensitive to noxious stimuli than age-matched control subjects. Fifty-two TMD patients (16 with muscle pain and 36 with combined muscle and joint pain) and 23 age-matched and gender-matched volunteers participated. Forearm thermal pain threshold and tolerance values were determined. A submaximal effort tourniquet procedure was used to evoke ischemic muscle pain. Relative to control subjects, TMD patients had significantly lower thermal pain threshold, ischemic pain threshold, and ischemic pain tolerance values; and thermal pain tolerance values also tended to be lower. Pain sensitivity did not differ between the two groups of TMD patients. Furthermore, the submaximal effort tourniquet procedure, which is capable of altering acute orofacial pain (Sigurdsson and Maixner, 1994) did not produce a consistent reduction in orofacial pain associated with TMD. We concluded that TMD patients are more sensitive to noxious stimuli than pain-free controls. These findings provide additional evidence that TMD is a psychophysiological disorder of the central nervous system which modulates emotional, physiological and neuroendocrine responses to emotional and physical stressors.",
keywords = "Myofascial pain, Pain sensitivity, Temporomandibular disorder, Temporomandibular joint disorder",
author = "William Maixner and Roger Fillingim and Donna Booker and Asgeir Sigurdsson",
year = "1995",
doi = "10.1016/0304-3959(95)00068-2",
language = "English (US)",
volume = "63",
pages = "341--351",
journal = "Pain",
issn = "0304-3959",
publisher = "Elsevier",
number = "3",

}

TY - JOUR

T1 - Sensitivity of patients with painful temporomandibular disorders to experimentally evoked pain

AU - Maixner, William

AU - Fillingim, Roger

AU - Booker, Donna

AU - Sigurdsson, Asgeir

PY - 1995

Y1 - 1995

N2 - Temporomandibular disorders (TMD) represent a group of chronic painful conditions involving the muscles of mastication and the temporomandibular joint. We determined whether patients with painful TMD are more sensitive to noxious stimuli than age-matched control subjects. Fifty-two TMD patients (16 with muscle pain and 36 with combined muscle and joint pain) and 23 age-matched and gender-matched volunteers participated. Forearm thermal pain threshold and tolerance values were determined. A submaximal effort tourniquet procedure was used to evoke ischemic muscle pain. Relative to control subjects, TMD patients had significantly lower thermal pain threshold, ischemic pain threshold, and ischemic pain tolerance values; and thermal pain tolerance values also tended to be lower. Pain sensitivity did not differ between the two groups of TMD patients. Furthermore, the submaximal effort tourniquet procedure, which is capable of altering acute orofacial pain (Sigurdsson and Maixner, 1994) did not produce a consistent reduction in orofacial pain associated with TMD. We concluded that TMD patients are more sensitive to noxious stimuli than pain-free controls. These findings provide additional evidence that TMD is a psychophysiological disorder of the central nervous system which modulates emotional, physiological and neuroendocrine responses to emotional and physical stressors.

AB - Temporomandibular disorders (TMD) represent a group of chronic painful conditions involving the muscles of mastication and the temporomandibular joint. We determined whether patients with painful TMD are more sensitive to noxious stimuli than age-matched control subjects. Fifty-two TMD patients (16 with muscle pain and 36 with combined muscle and joint pain) and 23 age-matched and gender-matched volunteers participated. Forearm thermal pain threshold and tolerance values were determined. A submaximal effort tourniquet procedure was used to evoke ischemic muscle pain. Relative to control subjects, TMD patients had significantly lower thermal pain threshold, ischemic pain threshold, and ischemic pain tolerance values; and thermal pain tolerance values also tended to be lower. Pain sensitivity did not differ between the two groups of TMD patients. Furthermore, the submaximal effort tourniquet procedure, which is capable of altering acute orofacial pain (Sigurdsson and Maixner, 1994) did not produce a consistent reduction in orofacial pain associated with TMD. We concluded that TMD patients are more sensitive to noxious stimuli than pain-free controls. These findings provide additional evidence that TMD is a psychophysiological disorder of the central nervous system which modulates emotional, physiological and neuroendocrine responses to emotional and physical stressors.

KW - Myofascial pain

KW - Pain sensitivity

KW - Temporomandibular disorder

KW - Temporomandibular joint disorder

UR - http://www.scopus.com/inward/record.url?scp=0028788568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028788568&partnerID=8YFLogxK

U2 - 10.1016/0304-3959(95)00068-2

DO - 10.1016/0304-3959(95)00068-2

M3 - Article

VL - 63

SP - 341

EP - 351

JO - Pain

JF - Pain

SN - 0304-3959

IS - 3

ER -