Scale-invariant spatial patterns in genome organization

Research output: Contribution to journalArticle

Abstract

Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.

Original languageEnglish (US)
Pages (from-to)252-256
Number of pages5
JournalPhysics Letters A
Volume175
Issue number3-4
DOIs
StatePublished - Apr 12 1993

Fingerprint

genome
fractals
coding
scaling

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Cite this

Scale-invariant spatial patterns in genome organization. / Purugganan, Michael D.

In: Physics Letters A, Vol. 175, No. 3-4, 12.04.1993, p. 252-256.

Research output: Contribution to journalArticle

@article{b527085e42f04f849db6755a61dbe609,
title = "Scale-invariant spatial patterns in genome organization",
abstract = "Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.",
author = "Purugganan, {Michael D.}",
year = "1993",
month = "4",
day = "12",
doi = "10.1016/0375-9601(93)90836-O",
language = "English (US)",
volume = "175",
pages = "252--256",
journal = "Physics Letters, Section A: General, Atomic and Solid State Physics",
issn = "0375-9601",
publisher = "Elsevier",
number = "3-4",

}

TY - JOUR

T1 - Scale-invariant spatial patterns in genome organization

AU - Purugganan, Michael D.

PY - 1993/4/12

Y1 - 1993/4/12

N2 - Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.

AB - Eukaryotic genomes are characterized by coding regions interspersed within non-coding sequences, creating irregular dispersal patterns. Fractal analysis was applied to the study of this dispersed organization of eukaryotic genomes. The results show that eukaryotic genomes possess two length regimes - a short ordered length scale, and a fractal regime with fractal dimensions ranging from 0.21±0.02 to 0.84±0.02. Fractal scaling provides clues to the origin and evolution of sequence patterns within genomes, and provides us with tools necessary to characterize such patterns in detail.

UR - http://www.scopus.com/inward/record.url?scp=24644515199&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=24644515199&partnerID=8YFLogxK

U2 - 10.1016/0375-9601(93)90836-O

DO - 10.1016/0375-9601(93)90836-O

M3 - Article

AN - SCOPUS:24644515199

VL - 175

SP - 252

EP - 256

JO - Physics Letters, Section A: General, Atomic and Solid State Physics

JF - Physics Letters, Section A: General, Atomic and Solid State Physics

SN - 0375-9601

IS - 3-4

ER -