RNA double helices generated from crystal structures of double helical dinucleoside phosphates

John M. Rosenberg, Nadrian C. Seeman, Roberta O. Day, Alexander Rich

Research output: Contribution to journalArticle


The dinucleoside phosphates ApU and GpC form right-handed anti-parallel double helical fragments within their crystal lattices. Using a least squares procedure, we have generated the extended double helices which these fragments represent. ApU corresponds to a double helix with 11.9 residues per turn and a pitch of 28. 1Å. The GpC double helix has 10.4 residues per turn and a pitch of 26. 9Å.

Original languageEnglish (US)
Pages (from-to)979-987
Number of pages9
JournalBiochemical and Biophysical Research Communications
Issue number4
StatePublished - Apr 19 1976


ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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