Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City

M. Marmor, Don Des Jarlais, H. Cohen, S. R. Friedman, S. T. Beatrice, N. Dubin, W. El-Sadr, D. Mildvan, S. Yancovitz, U. Mathur, R. Holzman

Research output: Contribution to journalArticle

Abstract

We report here the results of a survey of 308 intravenous drug abusers recruited from hospital-based methadone maintenance or drug detoxification programmes located in Manhattan, New York City. Complete interviews and serological analyses for antibodies to human immunodeficiency virus (HIV) using both enzyme-linked immunosorbent and Western blot assays were obtained from 290 (94%) of the subjects. HIV antibodies were found by both assays in 147 (50.7%) of the tested subjects; conflicting results were found in three (1%) of the subjects; and negative results on both tests were found in 140 (48.3%) of the subjects. Logistic regression analysis identified significant relative risks for HIV infection associated with the frequency of drug injection and the proportion of injections in 'shooting galleries'. Additional risk among men was associated with a history of homosexual relations. Traditional efforts taken by subjects to clean syringes between uses, such as washing with water or alcohol, showed no evidence of being protective. Programmes aimed at prevention of HIV infection should focus on reducing use of shooting galleries and sharing of needles and syringes as well as reducing intravenous drug abuse generally.

Original languageEnglish (US)
Pages (from-to)39-44
Number of pages6
JournalAIDS
Volume1
Issue number1
StatePublished - Dec 1 1987

Fingerprint

Drug Users
HIV
Needle Sharing
Virus Diseases
Infection
Intravenous Substance Abuse
Immunosorbents
Injections
Antibodies
Methadone
Syringes
Pharmaceutical Preparations
Logistic Models
Western Blotting
Regression Analysis
Alcohols
Interviews
Water
Enzymes

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Infectious Diseases

Cite this

Marmor, M., Des Jarlais, D., Cohen, H., Friedman, S. R., Beatrice, S. T., Dubin, N., ... Holzman, R. (1987). Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City. AIDS, 1(1), 39-44.

Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City. / Marmor, M.; Des Jarlais, Don; Cohen, H.; Friedman, S. R.; Beatrice, S. T.; Dubin, N.; El-Sadr, W.; Mildvan, D.; Yancovitz, S.; Mathur, U.; Holzman, R.

In: AIDS, Vol. 1, No. 1, 01.12.1987, p. 39-44.

Research output: Contribution to journalArticle

Marmor, M, Des Jarlais, D, Cohen, H, Friedman, SR, Beatrice, ST, Dubin, N, El-Sadr, W, Mildvan, D, Yancovitz, S, Mathur, U & Holzman, R 1987, 'Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City', AIDS, vol. 1, no. 1, pp. 39-44.
Marmor M, Des Jarlais D, Cohen H, Friedman SR, Beatrice ST, Dubin N et al. Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City. AIDS. 1987 Dec 1;1(1):39-44.
Marmor, M. ; Des Jarlais, Don ; Cohen, H. ; Friedman, S. R. ; Beatrice, S. T. ; Dubin, N. ; El-Sadr, W. ; Mildvan, D. ; Yancovitz, S. ; Mathur, U. ; Holzman, R. / Risk factors for infection with human immunodeficiency virus among intravenous drug abusers in New York City. In: AIDS. 1987 ; Vol. 1, No. 1. pp. 39-44.
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