Risk factors for adult-onset recurrent respiratory papillomatosis

Ryan Ruiz, Stratos Achlatis, Avanti Verma, Hayley Born, Farzana Kapadia, Yixin Fang, Michael Pitman, Lucian Sulica, Ryan C. Branski, Milan R. Amin

Research output: Contribution to journalArticle

Abstract

Objectives/Hypothesis: To evaluate risk factors strongly associated with adult-onset recurrent respiratory papillomatosis (AO-RRP). Study Design: Prospective, age- and sex-matched, case control. Methods: Patients with AO-RRP and controls completed a computer-based, 89-item questionnaire across three academic institutions. Results: Forty-eight AO-RRP patients were compared to 73 controls; 43 of the 48 AO-RRP patients were male (89.5%). The difference in the median number of lifetime sexual partners between AO-RRP (15) and controls (10) was significant (P = 0.0387). Additionally, an increased number of lifetime sexual partners (≥ 26) was associated with AO-RRP. No significant difference for the number of lifetime oral sex partners was observed between groups. Increased comorbidity, as quantified by the Charlson Comorbidity Index, was observed in patients with AO-RRP. AO-RRP and control groups were similar across many other variables, including birth history, smoking history, alcohol use, drug use, education, income, and the Short Form Health Survey scores. Conclusions: AO-RRP was not associated with previously proposed risk factors for juvenile-onset RRP and may be associated with an increased number of lifetime sexual partners.

Original languageEnglish (US)
Pages (from-to)2338-2344
Number of pages7
JournalLaryngoscope
Volume124
Issue number10
DOIs
StatePublished - Oct 1 2014

Fingerprint

Sexual Partners
Comorbidity
Recurrent respiratory papillomatosis
Reproductive History
Health Surveys
Sexual Behavior
Smoking
History
Alcohols
Prospective Studies
Education
Control Groups
Pharmaceutical Preparations

Keywords

  • Human papillomavirus
  • Larynx
  • Recurrent respiratory papillomatosis
  • Voice

ASJC Scopus subject areas

  • Otorhinolaryngology
  • Medicine(all)

Cite this

Ruiz, R., Achlatis, S., Verma, A., Born, H., Kapadia, F., Fang, Y., ... Amin, M. R. (2014). Risk factors for adult-onset recurrent respiratory papillomatosis. Laryngoscope, 124(10), 2338-2344. https://doi.org/10.1002/lary.24730

Risk factors for adult-onset recurrent respiratory papillomatosis. / Ruiz, Ryan; Achlatis, Stratos; Verma, Avanti; Born, Hayley; Kapadia, Farzana; Fang, Yixin; Pitman, Michael; Sulica, Lucian; Branski, Ryan C.; Amin, Milan R.

In: Laryngoscope, Vol. 124, No. 10, 01.10.2014, p. 2338-2344.

Research output: Contribution to journalArticle

Ruiz, R, Achlatis, S, Verma, A, Born, H, Kapadia, F, Fang, Y, Pitman, M, Sulica, L, Branski, RC & Amin, MR 2014, 'Risk factors for adult-onset recurrent respiratory papillomatosis', Laryngoscope, vol. 124, no. 10, pp. 2338-2344. https://doi.org/10.1002/lary.24730
Ruiz R, Achlatis S, Verma A, Born H, Kapadia F, Fang Y et al. Risk factors for adult-onset recurrent respiratory papillomatosis. Laryngoscope. 2014 Oct 1;124(10):2338-2344. https://doi.org/10.1002/lary.24730
Ruiz, Ryan ; Achlatis, Stratos ; Verma, Avanti ; Born, Hayley ; Kapadia, Farzana ; Fang, Yixin ; Pitman, Michael ; Sulica, Lucian ; Branski, Ryan C. ; Amin, Milan R. / Risk factors for adult-onset recurrent respiratory papillomatosis. In: Laryngoscope. 2014 ; Vol. 124, No. 10. pp. 2338-2344.
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