Reward value-based gain control

Divisive normalization in parietal cortex

Kenway Louie, Lauren E. Grattan, Paul Glimcher

Research output: Contribution to journalArticle

Abstract

The representation of value is a critical component of decision making. Rational choice theory assumes that options are assigned absolute values, independent of the value or existence of other alternatives. However, context-dependent choice behavior in both animals and humans violates this assumption, suggesting that biological decision processes rely on comparative evaluation. Here we show that neurons in the monkey lateral intraparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of the other available alternatives. Analogous to extra-classical receptive field effects in visual cortex, this relative representation incorporates target values outside the response field and is observed in both stimulus-driven activity and baseline firing rates. This context-dependent modulation is precisely described by divisive normalization, indicating that this standard form of sensory gain control may be a general mechanism of cortical computation. Such normalization in decision circuits effectively implements an adaptive gain control for value coding and provides a possible mechanistic basis for behavioral contextdependent violations of rationality.

Original languageEnglish (US)
Pages (from-to)10627-10639
Number of pages13
JournalJournal of Neuroscience
Volume31
Issue number29
DOIs
StatePublished - Jul 20 2011

Fingerprint

Choice Behavior
Biological Phenomena
Parietal Lobe
Visual Cortex
Reward
Haplorhini
Decision Making
Neurons

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Reward value-based gain control : Divisive normalization in parietal cortex. / Louie, Kenway; Grattan, Lauren E.; Glimcher, Paul.

In: Journal of Neuroscience, Vol. 31, No. 29, 20.07.2011, p. 10627-10639.

Research output: Contribution to journalArticle

Louie, Kenway ; Grattan, Lauren E. ; Glimcher, Paul. / Reward value-based gain control : Divisive normalization in parietal cortex. In: Journal of Neuroscience. 2011 ; Vol. 31, No. 29. pp. 10627-10639.
@article{0e20c6d6576d4e18af176e4969256edd,
title = "Reward value-based gain control: Divisive normalization in parietal cortex",
abstract = "The representation of value is a critical component of decision making. Rational choice theory assumes that options are assigned absolute values, independent of the value or existence of other alternatives. However, context-dependent choice behavior in both animals and humans violates this assumption, suggesting that biological decision processes rely on comparative evaluation. Here we show that neurons in the monkey lateral intraparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of the other available alternatives. Analogous to extra-classical receptive field effects in visual cortex, this relative representation incorporates target values outside the response field and is observed in both stimulus-driven activity and baseline firing rates. This context-dependent modulation is precisely described by divisive normalization, indicating that this standard form of sensory gain control may be a general mechanism of cortical computation. Such normalization in decision circuits effectively implements an adaptive gain control for value coding and provides a possible mechanistic basis for behavioral contextdependent violations of rationality.",
author = "Kenway Louie and Grattan, {Lauren E.} and Paul Glimcher",
year = "2011",
month = "7",
day = "20",
doi = "10.1523/JNEUROSCI.1237-11.2011",
language = "English (US)",
volume = "31",
pages = "10627--10639",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "29",

}

TY - JOUR

T1 - Reward value-based gain control

T2 - Divisive normalization in parietal cortex

AU - Louie, Kenway

AU - Grattan, Lauren E.

AU - Glimcher, Paul

PY - 2011/7/20

Y1 - 2011/7/20

N2 - The representation of value is a critical component of decision making. Rational choice theory assumes that options are assigned absolute values, independent of the value or existence of other alternatives. However, context-dependent choice behavior in both animals and humans violates this assumption, suggesting that biological decision processes rely on comparative evaluation. Here we show that neurons in the monkey lateral intraparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of the other available alternatives. Analogous to extra-classical receptive field effects in visual cortex, this relative representation incorporates target values outside the response field and is observed in both stimulus-driven activity and baseline firing rates. This context-dependent modulation is precisely described by divisive normalization, indicating that this standard form of sensory gain control may be a general mechanism of cortical computation. Such normalization in decision circuits effectively implements an adaptive gain control for value coding and provides a possible mechanistic basis for behavioral contextdependent violations of rationality.

AB - The representation of value is a critical component of decision making. Rational choice theory assumes that options are assigned absolute values, independent of the value or existence of other alternatives. However, context-dependent choice behavior in both animals and humans violates this assumption, suggesting that biological decision processes rely on comparative evaluation. Here we show that neurons in the monkey lateral intraparietal cortex encode a relative form of saccadic value, explicitly dependent on the values of the other available alternatives. Analogous to extra-classical receptive field effects in visual cortex, this relative representation incorporates target values outside the response field and is observed in both stimulus-driven activity and baseline firing rates. This context-dependent modulation is precisely described by divisive normalization, indicating that this standard form of sensory gain control may be a general mechanism of cortical computation. Such normalization in decision circuits effectively implements an adaptive gain control for value coding and provides a possible mechanistic basis for behavioral contextdependent violations of rationality.

UR - http://www.scopus.com/inward/record.url?scp=79960661918&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79960661918&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.1237-11.2011

DO - 10.1523/JNEUROSCI.1237-11.2011

M3 - Article

VL - 31

SP - 10627

EP - 10639

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 29

ER -