Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors

Matthew Volgraf, Pau Gorostiza, Stephanie Szobota, Max R. Helix, Ehud Y. Isacoff, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

The design, synthesis, and biological evaluation of a photochromic glutamate analogue is described. The molecule functions as a reversibly caged neurotransmitter and can be used to influence neural activity with light.

Original languageEnglish (US)
Pages (from-to)260-261
Number of pages2
JournalJournal of the American Chemical Society
Volume129
Issue number2
DOIs
StatePublished - Jan 17 2007

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Ionotropic Glutamate Receptors
Neurotransmitter Agents
Glutamic Acid
Light
Molecules

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Volgraf, M., Gorostiza, P., Szobota, S., Helix, M. R., Isacoff, E. Y., & Trauner, D. (2007). Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors. Journal of the American Chemical Society, 129(2), 260-261. https://doi.org/10.1021/ja067269o

Reversibly caged glutamate : A photochromic agonist of ionotropic glutamate receptors. / Volgraf, Matthew; Gorostiza, Pau; Szobota, Stephanie; Helix, Max R.; Isacoff, Ehud Y.; Trauner, Dirk.

In: Journal of the American Chemical Society, Vol. 129, No. 2, 17.01.2007, p. 260-261.

Research output: Contribution to journalArticle

Volgraf, M, Gorostiza, P, Szobota, S, Helix, MR, Isacoff, EY & Trauner, D 2007, 'Reversibly caged glutamate: A photochromic agonist of ionotropic glutamate receptors', Journal of the American Chemical Society, vol. 129, no. 2, pp. 260-261. https://doi.org/10.1021/ja067269o
Volgraf, Matthew ; Gorostiza, Pau ; Szobota, Stephanie ; Helix, Max R. ; Isacoff, Ehud Y. ; Trauner, Dirk. / Reversibly caged glutamate : A photochromic agonist of ionotropic glutamate receptors. In: Journal of the American Chemical Society. 2007 ; Vol. 129, No. 2. pp. 260-261.
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