Responses of ventral posterior thalamus neurons to three-dimensional vestibular and optic flow stimulation

Hui Meng, Dora Angelaki

Research output: Contribution to journalArticle

Abstract

Multisensory neurons tuned to both vestibular and visual motion (optic flow) signals are found in several cortical areas in the dorsal visual stream. Here we examine whether such convergence occurs subcortically in the macaque thalamus. We searched the ventral posterior nuclei, including the anterior pulvinar, as well as the ventro-lateral and ventral posterior lateral nuclei, areas that receive vestibular signals from brain stem and deep cerebellar nuclei. Approximately a quarter of cells responded to three-dimensional (3D) translational and/or rotational motion. More than half of the responsive cells were convergent, thus responded during both rotation and translation. The preferred axes of translation/rotation were distributed throughout 3D space. The majority of the neurons were excited, but some were inhibited, during rotation/translation in darkness. Only a couple of neurons were multisensory being tuned to both vestibular and optic flow stimuli. We conclude that multisensory vestibular/optic flow neurons, which are commonly found in cortical visual and visuomotor areas, are rare in the ventral posterior thalamus.

Original languageEnglish (US)
Pages (from-to)817-826
Number of pages10
JournalJournal of Neurophysiology
Volume103
Issue number2
DOIs
StatePublished - Feb 1 2010

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Optic Flow
Ventral Thalamic Nuclei
Thalamus
Neurons
Pulvinar
Cerebellar Nuclei
Darkness
Macaca
Brain Stem

ASJC Scopus subject areas

  • Physiology
  • Neuroscience(all)

Cite this

Responses of ventral posterior thalamus neurons to three-dimensional vestibular and optic flow stimulation. / Meng, Hui; Angelaki, Dora.

In: Journal of Neurophysiology, Vol. 103, No. 2, 01.02.2010, p. 817-826.

Research output: Contribution to journalArticle

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