Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex

Sheng Liu, J. David Dickman, Dora Angelaki

Research output: Contribution to journalArticle

Abstract

The parietoinsular vestibular cortex (PIVC) is a large area in the lateral sulcus with neurons that respond to vestibular stimulation. Here we compare the properties of PIVC cells with those of neurons in brain stem, cerebellum, and thalamus. Most PIVC cells modulated during both translational and rotational head motion. Translation acceleration gains showed a modest decrease as stimulus frequency increased, with a steeper slope than that reported previously for thalamic and cerebellar nuclei neurons. Response dynamics during yaw rotation were similar to those reported for vestibular neurons in brain stem and thalamus: velocity gains were relatively flat through the mid-frequency range, increased at high frequencies, and decreased at low frequencies. Tilt dynamics were more variable: PIVC neurons responsive only to rotation had gains that decreased with increased frequency, whereas neurons responsive during both translation and rotation (convergent neurons) actually increased their modulation magnitude at high frequencies. Using combinations of translation and tilt, most PIVC neurons were better correlated with translational motion; only 14% were better correlated with net acceleration. Thus, although yaw rotation responses in PIVC appear little processed compared with other central vestibular neurons, translation and tilt responses suggest a further processing of linear acceleration signals in thalamocortical circuits.

Original languageEnglish (US)
Pages (from-to)563-573
Number of pages11
JournalCerebral Cortex
Volume21
Issue number3
DOIs
StatePublished - Mar 1 2011

Fingerprint

Neurons
Yaws
Thalamus
Brain Stem
Cerebellar Nuclei
Thalamic Nuclei
Cerebellum
Head

Keywords

  • computation
  • cortex
  • lateral sulcus
  • PIVC
  • rotation
  • translation
  • vestibular

ASJC Scopus subject areas

  • Cognitive Neuroscience
  • Cellular and Molecular Neuroscience

Cite this

Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex. / Liu, Sheng; Dickman, J. David; Angelaki, Dora.

In: Cerebral Cortex, Vol. 21, No. 3, 01.03.2011, p. 563-573.

Research output: Contribution to journalArticle

@article{48c49592fbb04fcaa8c52f8c2a9aafea,
title = "Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex",
abstract = "The parietoinsular vestibular cortex (PIVC) is a large area in the lateral sulcus with neurons that respond to vestibular stimulation. Here we compare the properties of PIVC cells with those of neurons in brain stem, cerebellum, and thalamus. Most PIVC cells modulated during both translational and rotational head motion. Translation acceleration gains showed a modest decrease as stimulus frequency increased, with a steeper slope than that reported previously for thalamic and cerebellar nuclei neurons. Response dynamics during yaw rotation were similar to those reported for vestibular neurons in brain stem and thalamus: velocity gains were relatively flat through the mid-frequency range, increased at high frequencies, and decreased at low frequencies. Tilt dynamics were more variable: PIVC neurons responsive only to rotation had gains that decreased with increased frequency, whereas neurons responsive during both translation and rotation (convergent neurons) actually increased their modulation magnitude at high frequencies. Using combinations of translation and tilt, most PIVC neurons were better correlated with translational motion; only 14{\%} were better correlated with net acceleration. Thus, although yaw rotation responses in PIVC appear little processed compared with other central vestibular neurons, translation and tilt responses suggest a further processing of linear acceleration signals in thalamocortical circuits.",
keywords = "computation, cortex, lateral sulcus, PIVC, rotation, translation, vestibular",
author = "Sheng Liu and Dickman, {J. David} and Dora Angelaki",
year = "2011",
month = "3",
day = "1",
doi = "10.1093/cercor/bhq123",
language = "English (US)",
volume = "21",
pages = "563--573",
journal = "Cerebral Cortex",
issn = "1047-3211",
publisher = "Oxford University Press",
number = "3",

}

TY - JOUR

T1 - Response dynamics and tilt versus translation discrimination in parietoinsular vestibular cortex

AU - Liu, Sheng

AU - Dickman, J. David

AU - Angelaki, Dora

PY - 2011/3/1

Y1 - 2011/3/1

N2 - The parietoinsular vestibular cortex (PIVC) is a large area in the lateral sulcus with neurons that respond to vestibular stimulation. Here we compare the properties of PIVC cells with those of neurons in brain stem, cerebellum, and thalamus. Most PIVC cells modulated during both translational and rotational head motion. Translation acceleration gains showed a modest decrease as stimulus frequency increased, with a steeper slope than that reported previously for thalamic and cerebellar nuclei neurons. Response dynamics during yaw rotation were similar to those reported for vestibular neurons in brain stem and thalamus: velocity gains were relatively flat through the mid-frequency range, increased at high frequencies, and decreased at low frequencies. Tilt dynamics were more variable: PIVC neurons responsive only to rotation had gains that decreased with increased frequency, whereas neurons responsive during both translation and rotation (convergent neurons) actually increased their modulation magnitude at high frequencies. Using combinations of translation and tilt, most PIVC neurons were better correlated with translational motion; only 14% were better correlated with net acceleration. Thus, although yaw rotation responses in PIVC appear little processed compared with other central vestibular neurons, translation and tilt responses suggest a further processing of linear acceleration signals in thalamocortical circuits.

AB - The parietoinsular vestibular cortex (PIVC) is a large area in the lateral sulcus with neurons that respond to vestibular stimulation. Here we compare the properties of PIVC cells with those of neurons in brain stem, cerebellum, and thalamus. Most PIVC cells modulated during both translational and rotational head motion. Translation acceleration gains showed a modest decrease as stimulus frequency increased, with a steeper slope than that reported previously for thalamic and cerebellar nuclei neurons. Response dynamics during yaw rotation were similar to those reported for vestibular neurons in brain stem and thalamus: velocity gains were relatively flat through the mid-frequency range, increased at high frequencies, and decreased at low frequencies. Tilt dynamics were more variable: PIVC neurons responsive only to rotation had gains that decreased with increased frequency, whereas neurons responsive during both translation and rotation (convergent neurons) actually increased their modulation magnitude at high frequencies. Using combinations of translation and tilt, most PIVC neurons were better correlated with translational motion; only 14% were better correlated with net acceleration. Thus, although yaw rotation responses in PIVC appear little processed compared with other central vestibular neurons, translation and tilt responses suggest a further processing of linear acceleration signals in thalamocortical circuits.

KW - computation

KW - cortex

KW - lateral sulcus

KW - PIVC

KW - rotation

KW - translation

KW - vestibular

UR - http://www.scopus.com/inward/record.url?scp=79951841750&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=79951841750&partnerID=8YFLogxK

U2 - 10.1093/cercor/bhq123

DO - 10.1093/cercor/bhq123

M3 - Article

VL - 21

SP - 563

EP - 573

JO - Cerebral Cortex

JF - Cerebral Cortex

SN - 1047-3211

IS - 3

ER -