Reconsolidation of Pavlovian Conditioned Defense Responses in the Amygdala

Jacek Debiec, Joseph Ledoux

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The ability to learn about adverse events has a special significance for survival. A body of work established the key role of the amygdala in acquisition, consolidation, and extinction of defense (fear) responses that protect the organism in the presence of learned threats. More than a decade ago, our lab showed that exposure to a learned threat, leading to the retrieval or reactivation of the memory, leads to a reconsolidation (re-storage) of the memory in the amygdala. This finding reinvigorated interest in the role of memory retrieval in memory stability and change. In this chapter, we summarize research on the role of the amygdala in defense learning and memory and then discuss memory reconsolidation in the amygdala and its theoretical and clinical implications.

Original languageEnglish (US)
Title of host publicationMemory Reconsolidation
PublisherElsevier Inc.
Pages69-79
Number of pages11
ISBN (Print)9780123868923
DOIs
StatePublished - 2013

Fingerprint

Amygdala
Aptitude
Fear
Learning
Research

Keywords

  • Amygdala
  • Consolidation
  • Emotion
  • Extinction
  • Fear
  • Memory
  • Reconsolidation

ASJC Scopus subject areas

  • Psychology(all)

Cite this

Reconsolidation of Pavlovian Conditioned Defense Responses in the Amygdala. / Debiec, Jacek; Ledoux, Joseph.

Memory Reconsolidation. Elsevier Inc., 2013. p. 69-79.

Research output: Chapter in Book/Report/Conference proceedingChapter

Debiec, Jacek ; Ledoux, Joseph. / Reconsolidation of Pavlovian Conditioned Defense Responses in the Amygdala. Memory Reconsolidation. Elsevier Inc., 2013. pp. 69-79
@inbook{8962cf4fc4c34a5abc1c1592e0d9904f,
title = "Reconsolidation of Pavlovian Conditioned Defense Responses in the Amygdala",
abstract = "The ability to learn about adverse events has a special significance for survival. A body of work established the key role of the amygdala in acquisition, consolidation, and extinction of defense (fear) responses that protect the organism in the presence of learned threats. More than a decade ago, our lab showed that exposure to a learned threat, leading to the retrieval or reactivation of the memory, leads to a reconsolidation (re-storage) of the memory in the amygdala. This finding reinvigorated interest in the role of memory retrieval in memory stability and change. In this chapter, we summarize research on the role of the amygdala in defense learning and memory and then discuss memory reconsolidation in the amygdala and its theoretical and clinical implications.",
keywords = "Amygdala, Consolidation, Emotion, Extinction, Fear, Memory, Reconsolidation",
author = "Jacek Debiec and Joseph Ledoux",
year = "2013",
doi = "10.1016/B978-0-12-386892-3.00004-4",
language = "English (US)",
isbn = "9780123868923",
pages = "69--79",
booktitle = "Memory Reconsolidation",
publisher = "Elsevier Inc.",

}

TY - CHAP

T1 - Reconsolidation of Pavlovian Conditioned Defense Responses in the Amygdala

AU - Debiec, Jacek

AU - Ledoux, Joseph

PY - 2013

Y1 - 2013

N2 - The ability to learn about adverse events has a special significance for survival. A body of work established the key role of the amygdala in acquisition, consolidation, and extinction of defense (fear) responses that protect the organism in the presence of learned threats. More than a decade ago, our lab showed that exposure to a learned threat, leading to the retrieval or reactivation of the memory, leads to a reconsolidation (re-storage) of the memory in the amygdala. This finding reinvigorated interest in the role of memory retrieval in memory stability and change. In this chapter, we summarize research on the role of the amygdala in defense learning and memory and then discuss memory reconsolidation in the amygdala and its theoretical and clinical implications.

AB - The ability to learn about adverse events has a special significance for survival. A body of work established the key role of the amygdala in acquisition, consolidation, and extinction of defense (fear) responses that protect the organism in the presence of learned threats. More than a decade ago, our lab showed that exposure to a learned threat, leading to the retrieval or reactivation of the memory, leads to a reconsolidation (re-storage) of the memory in the amygdala. This finding reinvigorated interest in the role of memory retrieval in memory stability and change. In this chapter, we summarize research on the role of the amygdala in defense learning and memory and then discuss memory reconsolidation in the amygdala and its theoretical and clinical implications.

KW - Amygdala

KW - Consolidation

KW - Emotion

KW - Extinction

KW - Fear

KW - Memory

KW - Reconsolidation

UR - http://www.scopus.com/inward/record.url?scp=84882711693&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84882711693&partnerID=8YFLogxK

U2 - 10.1016/B978-0-12-386892-3.00004-4

DO - 10.1016/B978-0-12-386892-3.00004-4

M3 - Chapter

AN - SCOPUS:84882711693

SN - 9780123868923

SP - 69

EP - 79

BT - Memory Reconsolidation

PB - Elsevier Inc.

ER -