Reciprocal DNA nanomechanical devices controlled by the same set strands

Chunhua Liu, Natasha Jonoska, Nadrian Seeman

Research output: Contribution to journalArticle

Abstract

Reciprocating devices are key features in macroscopic machines. We have adapted the DNA PX-JX 2 device to a reciprocal format. The PX-JX 2 device is a robust sequence-dependent nanomachine, whose state is established by a pair of control strands that set it to be either in the PX state or in the JX 2 state. The two states differ by a half-turn rotation between their ends. Here we report the construction of a pair of reciprocal PX-JX 2 devices, wherein the control strands leading to the PX state in one device lead to the JX 2 state in the other device and vice versa. The formation, transformation, and reciprocal motions of these two device systems are confirmed using gel electrophoresis and atomic force microscopy. This system is likely to be of use for molecular robotic applications where reciprocal motions are of value in addition its inherent contribution to molecular choreography and molecular aesthetics.

Original languageEnglish (US)
Pages (from-to)2641-2647
Number of pages7
JournalNano Letters
Volume9
Issue number7
DOIs
StatePublished - Jul 8 2009

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strands
DNA
deoxyribonucleic acid
Electrophoresis
Atomic force microscopy
Robotics
Gels
electrophoresis
robotics
format
atomic force microscopy
gels

ASJC Scopus subject areas

  • Bioengineering
  • Chemistry(all)
  • Mechanical Engineering
  • Materials Science(all)
  • Condensed Matter Physics

Cite this

Reciprocal DNA nanomechanical devices controlled by the same set strands. / Liu, Chunhua; Jonoska, Natasha; Seeman, Nadrian.

In: Nano Letters, Vol. 9, No. 7, 08.07.2009, p. 2641-2647.

Research output: Contribution to journalArticle

Liu, Chunhua ; Jonoska, Natasha ; Seeman, Nadrian. / Reciprocal DNA nanomechanical devices controlled by the same set strands. In: Nano Letters. 2009 ; Vol. 9, No. 7. pp. 2641-2647.
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