Reactivation of herpes simplex virus keratitis after initiating bimatoprost treatment for glaucoma

Debra M. Kroll, Joel S. Schuman

    Research output: Contribution to journalArticle

    Abstract

    PURPOSE: To report a case of herpes simplex virus reactivation after starting bimatoprost treatment for glaucoma. DESIGN: Interventional case report. METHODS: A 66-year-old woman had a herpes simplex keratouveitis reactivation that occurred within 1 month after starting bimatoprost. The herpes simplex had been inactive for more than 10 years. RESULTS: Bimatoprost and prednisolone acetate 0.12% were discontinued; oral acyclovir, ofloxacin, and betaxolol 0.25% were initiated. Two weeks later, prednisolone acetate 1% was added. The reactivation resolved, and 1 month later, the best corrected visual acuity improved to 20/40. CONCLUSION: Caution should be used in prescribing bimatoprost for patients with a history of herpes simplex virus keratitis.

    Original languageEnglish (US)
    Pages (from-to)401-403
    Number of pages3
    JournalAmerican Journal of Ophthalmology
    Volume133
    Issue number3
    DOIs
    StatePublished - Jan 1 2002

    ASJC Scopus subject areas

    • Ophthalmology

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