Reaching the Limit of the oculomotor plant: 3d kinematics after abducens nerve stimulation during the torsional vestibulo-ocular reflex

Eliana M. Klier, Hui Meng, Dora Angelaki

Research output: Contribution to journalArticle

Abstract

Accumulating evidence shows that the oculomotor plant is capable of implementing aspects of three-dimensional kinematics such as Listing's law and the half-angle rule. But these studies have only examined the eye under static conditions or with movements that normally obey these rules (e.g., saccades and pursuit). Here we test the capability of the oculomotor plant to rearrange itself as necessary for non-half-angle behavior. Three monkeys (Macaca mulatta) fixated five vertically displaced targets along the midsagittal plane while sitting on a motion platform that rotated sinusoidally about the naso-occipital axis. This activated the torsional, rotational vestibuloocular reflex, which exhibits a zero-angle or negative-angle rule (depending on the visual stimulus). On random sinusoidal cycles, we stimulated the abducens nerve and observed the resultant eye movements. If the plant has rearranged itself to implement this non-halfangle behavior, then stimulation should reveal this behavior. On the other hand, if the plant is only capable of half-angle behavior, then stimulation should reveal a half-angle rule. We find the latter to be true and therefore additional neural signals are likely necessary to implement non-half-angle behavior.

Original languageEnglish (US)
Pages (from-to)13237-13243
Number of pages7
JournalJournal of Neuroscience
Volume32
Issue number38
DOIs
StatePublished - Sep 19 2012

Fingerprint

Abducens Nerve
Vestibulo-Ocular Reflex
Biomechanical Phenomena
Saccades
Eye Movements
Macaca mulatta
Haplorhini

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Reaching the Limit of the oculomotor plant : 3d kinematics after abducens nerve stimulation during the torsional vestibulo-ocular reflex. / Klier, Eliana M.; Meng, Hui; Angelaki, Dora.

In: Journal of Neuroscience, Vol. 32, No. 38, 19.09.2012, p. 13237-13243.

Research output: Contribution to journalArticle

@article{4f640caccce4465c90d7781d9ecc158c,
title = "Reaching the Limit of the oculomotor plant: 3d kinematics after abducens nerve stimulation during the torsional vestibulo-ocular reflex",
abstract = "Accumulating evidence shows that the oculomotor plant is capable of implementing aspects of three-dimensional kinematics such as Listing's law and the half-angle rule. But these studies have only examined the eye under static conditions or with movements that normally obey these rules (e.g., saccades and pursuit). Here we test the capability of the oculomotor plant to rearrange itself as necessary for non-half-angle behavior. Three monkeys (Macaca mulatta) fixated five vertically displaced targets along the midsagittal plane while sitting on a motion platform that rotated sinusoidally about the naso-occipital axis. This activated the torsional, rotational vestibuloocular reflex, which exhibits a zero-angle or negative-angle rule (depending on the visual stimulus). On random sinusoidal cycles, we stimulated the abducens nerve and observed the resultant eye movements. If the plant has rearranged itself to implement this non-halfangle behavior, then stimulation should reveal this behavior. On the other hand, if the plant is only capable of half-angle behavior, then stimulation should reveal a half-angle rule. We find the latter to be true and therefore additional neural signals are likely necessary to implement non-half-angle behavior.",
author = "Klier, {Eliana M.} and Hui Meng and Dora Angelaki",
year = "2012",
month = "9",
day = "19",
doi = "10.1523/JNEUROSCI.2595-12.2012",
language = "English (US)",
volume = "32",
pages = "13237--13243",
journal = "Journal of Neuroscience",
issn = "0270-6474",
publisher = "Society for Neuroscience",
number = "38",

}

TY - JOUR

T1 - Reaching the Limit of the oculomotor plant

T2 - 3d kinematics after abducens nerve stimulation during the torsional vestibulo-ocular reflex

AU - Klier, Eliana M.

AU - Meng, Hui

AU - Angelaki, Dora

PY - 2012/9/19

Y1 - 2012/9/19

N2 - Accumulating evidence shows that the oculomotor plant is capable of implementing aspects of three-dimensional kinematics such as Listing's law and the half-angle rule. But these studies have only examined the eye under static conditions or with movements that normally obey these rules (e.g., saccades and pursuit). Here we test the capability of the oculomotor plant to rearrange itself as necessary for non-half-angle behavior. Three monkeys (Macaca mulatta) fixated five vertically displaced targets along the midsagittal plane while sitting on a motion platform that rotated sinusoidally about the naso-occipital axis. This activated the torsional, rotational vestibuloocular reflex, which exhibits a zero-angle or negative-angle rule (depending on the visual stimulus). On random sinusoidal cycles, we stimulated the abducens nerve and observed the resultant eye movements. If the plant has rearranged itself to implement this non-halfangle behavior, then stimulation should reveal this behavior. On the other hand, if the plant is only capable of half-angle behavior, then stimulation should reveal a half-angle rule. We find the latter to be true and therefore additional neural signals are likely necessary to implement non-half-angle behavior.

AB - Accumulating evidence shows that the oculomotor plant is capable of implementing aspects of three-dimensional kinematics such as Listing's law and the half-angle rule. But these studies have only examined the eye under static conditions or with movements that normally obey these rules (e.g., saccades and pursuit). Here we test the capability of the oculomotor plant to rearrange itself as necessary for non-half-angle behavior. Three monkeys (Macaca mulatta) fixated five vertically displaced targets along the midsagittal plane while sitting on a motion platform that rotated sinusoidally about the naso-occipital axis. This activated the torsional, rotational vestibuloocular reflex, which exhibits a zero-angle or negative-angle rule (depending on the visual stimulus). On random sinusoidal cycles, we stimulated the abducens nerve and observed the resultant eye movements. If the plant has rearranged itself to implement this non-halfangle behavior, then stimulation should reveal this behavior. On the other hand, if the plant is only capable of half-angle behavior, then stimulation should reveal a half-angle rule. We find the latter to be true and therefore additional neural signals are likely necessary to implement non-half-angle behavior.

UR - http://www.scopus.com/inward/record.url?scp=84866389230&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84866389230&partnerID=8YFLogxK

U2 - 10.1523/JNEUROSCI.2595-12.2012

DO - 10.1523/JNEUROSCI.2595-12.2012

M3 - Article

VL - 32

SP - 13237

EP - 13243

JO - Journal of Neuroscience

JF - Journal of Neuroscience

SN - 0270-6474

IS - 38

ER -