Ratiometric displacement approach to Cu(II) sensing by fluorescence

Maksim Royzen, Zhaohua Dai, James Canary

Research output: Contribution to journalArticle

Abstract

A chelation-enhanced fluorescence method for the detection of paramagnetic copper(II) ions is developed. Two dyes with unequal metal ion binding constants are used, each giving strong fluorescence enhancement in the presence of a diamagnetic reporter ion such as cadmium(II). Upon presentation of copper(II) to a 1:1:1 mixture of the two dyes and cadmium(II), the Cd(II) is displaced from one dye to the other, resulting in quenching of one dye by the Cu(II) and enhancement of the weaker binding dye by complexation of the Cd(II). Although several criteria must be met, this method holds promise for analysis of a wide range of analytes.

Original languageEnglish (US)
Pages (from-to)1612-1613
Number of pages2
JournalJournal of the American Chemical Society
Volume127
Issue number6
DOIs
StatePublished - Feb 16 2005

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Coloring Agents
Dyes
Fluorescence
Ions
Cadmium
Copper
Chelation
Complexation
Metal ions
Quenching
Metals

ASJC Scopus subject areas

  • Chemistry(all)

Cite this

Ratiometric displacement approach to Cu(II) sensing by fluorescence. / Royzen, Maksim; Dai, Zhaohua; Canary, James.

In: Journal of the American Chemical Society, Vol. 127, No. 6, 16.02.2005, p. 1612-1613.

Research output: Contribution to journalArticle

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