Quality of life for patients requiring surgical resection and reconstruction for mandibular osteoradionecrosis

10-year experience at the university of California San Francisco

Edward I. Chang, Pablo Leon, William Y. Hoffman, Brian Schmidt

Research output: Contribution to journalArticle

Abstract

Background Mandibular osteoradionecrosis is the most devastating complication after radiation therapy for head and neck malignancies. Quality of life (QOL) after surgical treatment is unclear. Methods A retrospective cohort analysis (1997-2007) was conducted of all patients treated at our institution for stage II and III mandibular osteoradionecrosis. Nineteen of 35 patients responded to a modified University of Washington QOL questionnaire. Twenty had undergone reconstruction using free flaps, and the remainder with plates, plates and local flaps, or debridement alone. Results Complications included 3 infections, 5 with hardware, 5 flap-specific, and 1 nonunion. Four patients had recurrent squamous cell carcinoma (SCC). The factors of greatest concern to patients were appearance, swallowing, and chewing. Average overall QOL was good to very good, and very good compared to preoperative. Conclusion Despite a 37% complication rate, a multidisciplinary team approach with adequate debridement, resection, and reconstruction can greatly improve QOL.

Original languageEnglish (US)
Pages (from-to)207-212
Number of pages6
JournalHead and Neck
Volume34
Issue number2
DOIs
StatePublished - Feb 2012

Fingerprint

Osteoradionecrosis
Mandibular Reconstruction
San Francisco
Quality of Life
Debridement
Free Tissue Flaps
Mastication
Deglutition
Squamous Cell Carcinoma
Cohort Studies
Neck
Radiotherapy
Head
Infection
Neoplasms

Keywords

  • mandibular osteoradionecrosis
  • oral surgery
  • quality of life
  • reconstruction

ASJC Scopus subject areas

  • Otorhinolaryngology

Cite this

Quality of life for patients requiring surgical resection and reconstruction for mandibular osteoradionecrosis : 10-year experience at the university of California San Francisco. / Chang, Edward I.; Leon, Pablo; Hoffman, William Y.; Schmidt, Brian.

In: Head and Neck, Vol. 34, No. 2, 02.2012, p. 207-212.

Research output: Contribution to journalArticle

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