Protein Surface Recognition by Rational Design

Nanomolar Ligands for Potassium Channels

Stefan N. Gradl, John P. Felix, Ehud Y. Isacoff, Maria L. Garcia, Dirk Trauner

Research output: Contribution to journalArticle

Abstract

The rational design and development of four-fold symmetrical ligands for potassium channels is described.

Original languageEnglish (US)
Pages (from-to)12668-12669
Number of pages2
JournalJournal of the American Chemical Society
Volume125
Issue number42
DOIs
StatePublished - Oct 22 2003

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Potassium Channels
Potassium
Membrane Proteins
Ligands
Proteins

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Cite this

Protein Surface Recognition by Rational Design : Nanomolar Ligands for Potassium Channels. / Gradl, Stefan N.; Felix, John P.; Isacoff, Ehud Y.; Garcia, Maria L.; Trauner, Dirk.

In: Journal of the American Chemical Society, Vol. 125, No. 42, 22.10.2003, p. 12668-12669.

Research output: Contribution to journalArticle

Gradl, Stefan N. ; Felix, John P. ; Isacoff, Ehud Y. ; Garcia, Maria L. ; Trauner, Dirk. / Protein Surface Recognition by Rational Design : Nanomolar Ligands for Potassium Channels. In: Journal of the American Chemical Society. 2003 ; Vol. 125, No. 42. pp. 12668-12669.
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