Prospects for circular dichroism detection of nonracemic extraterrestrial organic molecules

James Canary, A. E. Holmes, J. Liu

Research output: Contribution to journalArticle

Abstract

The use of circular dichroism is examined as a probe for the detection of nonracemic analytes on spacecraft explorations such as a planned mission to Titan. Advances in both instrument design and chemistry will be required to make such a method practicable. The focus of this paper is on chemical agents able to amplify the circular dichroism signal, which would simplify instrument problems and increase sensitivity. A classic phenomenon known as the Pfeiffer effect provides a conceptual strategy to achieve the necessary aims for chirality detection. Recent examples of Pfeiffer-related phenomena are discussed.

Original languageEnglish (US)
Pages (from-to)181-188
Number of pages8
JournalEnantiomer
Volume6
Issue number2-3
StatePublished - 2001

Fingerprint

Dichroism
Circular Dichroism
Spacecraft
Saturn
Molecules
Chirality

Keywords

  • Chiral sensors
  • Circular dichroism
  • Host-guest chemistry
  • Molecular recognition
  • Pfeiffer effect
  • Titan

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Biochemistry
  • Chemistry(all)
  • Organic Chemistry

Cite this

Prospects for circular dichroism detection of nonracemic extraterrestrial organic molecules. / Canary, James; Holmes, A. E.; Liu, J.

In: Enantiomer, Vol. 6, No. 2-3, 2001, p. 181-188.

Research output: Contribution to journalArticle

@article{77f1fd1913b240c098ab70d7421ad84b,
title = "Prospects for circular dichroism detection of nonracemic extraterrestrial organic molecules",
abstract = "The use of circular dichroism is examined as a probe for the detection of nonracemic analytes on spacecraft explorations such as a planned mission to Titan. Advances in both instrument design and chemistry will be required to make such a method practicable. The focus of this paper is on chemical agents able to amplify the circular dichroism signal, which would simplify instrument problems and increase sensitivity. A classic phenomenon known as the Pfeiffer effect provides a conceptual strategy to achieve the necessary aims for chirality detection. Recent examples of Pfeiffer-related phenomena are discussed.",
keywords = "Chiral sensors, Circular dichroism, Host-guest chemistry, Molecular recognition, Pfeiffer effect, Titan",
author = "James Canary and Holmes, {A. E.} and J. Liu",
year = "2001",
language = "English (US)",
volume = "6",
pages = "181--188",
journal = "Enantiomer",
issn = "1024-2430",
publisher = "Taylor and Francis Ltd.",
number = "2-3",

}

TY - JOUR

T1 - Prospects for circular dichroism detection of nonracemic extraterrestrial organic molecules

AU - Canary, James

AU - Holmes, A. E.

AU - Liu, J.

PY - 2001

Y1 - 2001

N2 - The use of circular dichroism is examined as a probe for the detection of nonracemic analytes on spacecraft explorations such as a planned mission to Titan. Advances in both instrument design and chemistry will be required to make such a method practicable. The focus of this paper is on chemical agents able to amplify the circular dichroism signal, which would simplify instrument problems and increase sensitivity. A classic phenomenon known as the Pfeiffer effect provides a conceptual strategy to achieve the necessary aims for chirality detection. Recent examples of Pfeiffer-related phenomena are discussed.

AB - The use of circular dichroism is examined as a probe for the detection of nonracemic analytes on spacecraft explorations such as a planned mission to Titan. Advances in both instrument design and chemistry will be required to make such a method practicable. The focus of this paper is on chemical agents able to amplify the circular dichroism signal, which would simplify instrument problems and increase sensitivity. A classic phenomenon known as the Pfeiffer effect provides a conceptual strategy to achieve the necessary aims for chirality detection. Recent examples of Pfeiffer-related phenomena are discussed.

KW - Chiral sensors

KW - Circular dichroism

KW - Host-guest chemistry

KW - Molecular recognition

KW - Pfeiffer effect

KW - Titan

UR - http://www.scopus.com/inward/record.url?scp=0034812633&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0034812633&partnerID=8YFLogxK

M3 - Article

VL - 6

SP - 181

EP - 188

JO - Enantiomer

JF - Enantiomer

SN - 1024-2430

IS - 2-3

ER -