Problem of signal contamination in interhemispheric dual-sided subdural electrodes

George Nune, Jonathan Winawer, Andreas M. Rauschecker, Mohammad Dastjerdi, Brett L. Foster, Brian Wandell, Josef Parvizi

Research output: Contribution to journalArticle

Abstract

Dual-sided subdural electrodes are used in the localization and lateralization of seizure-onset zones when the area of interest is within the interhemispheric fissure. We designed the current study to test the validity of the assumption that each side of the dual-sided electrodes records from the hemisphere it faces. We recorded with dual-sided strip and grid electrodes implanted in the occipital interhemispheric space in two patients with nonoccipital epilepsy during two visual stimulation tasks in which subjects were presented with visual stimuli in the ipsilateral or contralateral visual hemifields. Our findings show substantial contamination of recordings from the opposite hemisphere. Although, as expected, electrodes recording through the falx record faintly from the contralateral cortical surface, they unexpectedly pick up strong signals from the cortex behind them. Therefore, we conclude that these electrodes should not be used for lateralization of the origin of epileptic activity or evoked responses.

Original languageEnglish (US)
JournalEpilepsia
Volume52
Issue number11
DOIs
StatePublished - Nov 2011

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Electrodes
Photic Stimulation
Implanted Electrodes
Epilepsy
Seizures

Keywords

  • Electrocorticography (ECoG)
  • Epilepsy surgery
  • Subdural grid electrodes

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Nune, G., Winawer, J., Rauschecker, A. M., Dastjerdi, M., Foster, B. L., Wandell, B., & Parvizi, J. (2011). Problem of signal contamination in interhemispheric dual-sided subdural electrodes. Epilepsia, 52(11). https://doi.org/10.1111/j.1528-1167.2011.03284.x

Problem of signal contamination in interhemispheric dual-sided subdural electrodes. / Nune, George; Winawer, Jonathan; Rauschecker, Andreas M.; Dastjerdi, Mohammad; Foster, Brett L.; Wandell, Brian; Parvizi, Josef.

In: Epilepsia, Vol. 52, No. 11, 11.2011.

Research output: Contribution to journalArticle

Nune, G, Winawer, J, Rauschecker, AM, Dastjerdi, M, Foster, BL, Wandell, B & Parvizi, J 2011, 'Problem of signal contamination in interhemispheric dual-sided subdural electrodes', Epilepsia, vol. 52, no. 11. https://doi.org/10.1111/j.1528-1167.2011.03284.x
Nune G, Winawer J, Rauschecker AM, Dastjerdi M, Foster BL, Wandell B et al. Problem of signal contamination in interhemispheric dual-sided subdural electrodes. Epilepsia. 2011 Nov;52(11). https://doi.org/10.1111/j.1528-1167.2011.03284.x
Nune, George ; Winawer, Jonathan ; Rauschecker, Andreas M. ; Dastjerdi, Mohammad ; Foster, Brett L. ; Wandell, Brian ; Parvizi, Josef. / Problem of signal contamination in interhemispheric dual-sided subdural electrodes. In: Epilepsia. 2011 ; Vol. 52, No. 11.
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