Probiotics and immune response

Susanna Cunningham-Rundles, Siv Ahrné, Stig Bengmark, Rosemary Johann-Liang, Florence Marshall, Linda Metakis, Claudia Califano, Ann-Margaret Dunn-Navarra, Claudia Grassey, Gilberto Hinds, Joseph Cervia

Research output: Contribution to journalArticle

Abstract

Current evidence supports the concept that oral administration of probiotic lactobacilli may be therapeutic in preventing antibiotic-associated diarrhea in children and in reestablishing normal flora in the gastrointestinal tract. Children with human immunodeficiency virus (HIV) infections may have episodes of diarrhea and frequently experience malabsorption associated with possible bacterial overgrowth; together these may interact to produce the growth abnormalities characteristic of this group. The overall objective of this investigation has been to determine whether oral administration of the probiotic Lactobacillus plantarum 299v could improve nutrient status and promote growth in children congenitally exposed to HIV. In addition, the possible beneficial effect of Lactobacillus plantarum 299v in modulating immune response was evaluated. In preliminary results described here, we report on the ability of Lactobacillus plantarum 299v to colonize children with HIV and to elicit specific systemic immune response after oral supplementation.

Original languageEnglish (US)
JournalAmerican Journal of Gastroenterology
Volume95
Issue number1 SUPPL.
DOIs
StatePublished - Jan 2000

Fingerprint

Probiotics
Lactobacillus plantarum
HIV
Oral Administration
Diarrhea
Lactobacillus
Virus Diseases
Growth
Gastrointestinal Tract
Anti-Bacterial Agents
Food
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Cunningham-Rundles, S., Ahrné, S., Bengmark, S., Johann-Liang, R., Marshall, F., Metakis, L., ... Cervia, J. (2000). Probiotics and immune response. American Journal of Gastroenterology, 95(1 SUPPL.). https://doi.org/10.1016/S0002-9270(99)00813-8

Probiotics and immune response. / Cunningham-Rundles, Susanna; Ahrné, Siv; Bengmark, Stig; Johann-Liang, Rosemary; Marshall, Florence; Metakis, Linda; Califano, Claudia; Dunn-Navarra, Ann-Margaret; Grassey, Claudia; Hinds, Gilberto; Cervia, Joseph.

In: American Journal of Gastroenterology, Vol. 95, No. 1 SUPPL., 01.2000.

Research output: Contribution to journalArticle

Cunningham-Rundles, S, Ahrné, S, Bengmark, S, Johann-Liang, R, Marshall, F, Metakis, L, Califano, C, Dunn-Navarra, A-M, Grassey, C, Hinds, G & Cervia, J 2000, 'Probiotics and immune response', American Journal of Gastroenterology, vol. 95, no. 1 SUPPL.. https://doi.org/10.1016/S0002-9270(99)00813-8
Cunningham-Rundles S, Ahrné S, Bengmark S, Johann-Liang R, Marshall F, Metakis L et al. Probiotics and immune response. American Journal of Gastroenterology. 2000 Jan;95(1 SUPPL.). https://doi.org/10.1016/S0002-9270(99)00813-8
Cunningham-Rundles, Susanna ; Ahrné, Siv ; Bengmark, Stig ; Johann-Liang, Rosemary ; Marshall, Florence ; Metakis, Linda ; Califano, Claudia ; Dunn-Navarra, Ann-Margaret ; Grassey, Claudia ; Hinds, Gilberto ; Cervia, Joseph. / Probiotics and immune response. In: American Journal of Gastroenterology. 2000 ; Vol. 95, No. 1 SUPPL.
@article{020f5419a57a441bab8adc55a65aa117,
title = "Probiotics and immune response",
abstract = "Current evidence supports the concept that oral administration of probiotic lactobacilli may be therapeutic in preventing antibiotic-associated diarrhea in children and in reestablishing normal flora in the gastrointestinal tract. Children with human immunodeficiency virus (HIV) infections may have episodes of diarrhea and frequently experience malabsorption associated with possible bacterial overgrowth; together these may interact to produce the growth abnormalities characteristic of this group. The overall objective of this investigation has been to determine whether oral administration of the probiotic Lactobacillus plantarum 299v could improve nutrient status and promote growth in children congenitally exposed to HIV. In addition, the possible beneficial effect of Lactobacillus plantarum 299v in modulating immune response was evaluated. In preliminary results described here, we report on the ability of Lactobacillus plantarum 299v to colonize children with HIV and to elicit specific systemic immune response after oral supplementation.",
author = "Susanna Cunningham-Rundles and Siv Ahrn{\'e} and Stig Bengmark and Rosemary Johann-Liang and Florence Marshall and Linda Metakis and Claudia Califano and Ann-Margaret Dunn-Navarra and Claudia Grassey and Gilberto Hinds and Joseph Cervia",
year = "2000",
month = "1",
doi = "10.1016/S0002-9270(99)00813-8",
language = "English (US)",
volume = "95",
journal = "American Journal of Gastroenterology",
issn = "0002-9270",
publisher = "Nature Publishing Group",
number = "1 SUPPL.",

}

TY - JOUR

T1 - Probiotics and immune response

AU - Cunningham-Rundles, Susanna

AU - Ahrné, Siv

AU - Bengmark, Stig

AU - Johann-Liang, Rosemary

AU - Marshall, Florence

AU - Metakis, Linda

AU - Califano, Claudia

AU - Dunn-Navarra, Ann-Margaret

AU - Grassey, Claudia

AU - Hinds, Gilberto

AU - Cervia, Joseph

PY - 2000/1

Y1 - 2000/1

N2 - Current evidence supports the concept that oral administration of probiotic lactobacilli may be therapeutic in preventing antibiotic-associated diarrhea in children and in reestablishing normal flora in the gastrointestinal tract. Children with human immunodeficiency virus (HIV) infections may have episodes of diarrhea and frequently experience malabsorption associated with possible bacterial overgrowth; together these may interact to produce the growth abnormalities characteristic of this group. The overall objective of this investigation has been to determine whether oral administration of the probiotic Lactobacillus plantarum 299v could improve nutrient status and promote growth in children congenitally exposed to HIV. In addition, the possible beneficial effect of Lactobacillus plantarum 299v in modulating immune response was evaluated. In preliminary results described here, we report on the ability of Lactobacillus plantarum 299v to colonize children with HIV and to elicit specific systemic immune response after oral supplementation.

AB - Current evidence supports the concept that oral administration of probiotic lactobacilli may be therapeutic in preventing antibiotic-associated diarrhea in children and in reestablishing normal flora in the gastrointestinal tract. Children with human immunodeficiency virus (HIV) infections may have episodes of diarrhea and frequently experience malabsorption associated with possible bacterial overgrowth; together these may interact to produce the growth abnormalities characteristic of this group. The overall objective of this investigation has been to determine whether oral administration of the probiotic Lactobacillus plantarum 299v could improve nutrient status and promote growth in children congenitally exposed to HIV. In addition, the possible beneficial effect of Lactobacillus plantarum 299v in modulating immune response was evaluated. In preliminary results described here, we report on the ability of Lactobacillus plantarum 299v to colonize children with HIV and to elicit specific systemic immune response after oral supplementation.

UR - http://www.scopus.com/inward/record.url?scp=18544412664&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=18544412664&partnerID=8YFLogxK

U2 - 10.1016/S0002-9270(99)00813-8

DO - 10.1016/S0002-9270(99)00813-8

M3 - Article

C2 - 10634225

AN - SCOPUS:18544412664

VL - 95

JO - American Journal of Gastroenterology

JF - American Journal of Gastroenterology

SN - 0002-9270

IS - 1 SUPPL.

ER -