Preliminary study on biomechanics of vertebroplasty

A computational fluid dynamics and solid mechanics combined approach

Jeremy Teo, Shih Chang Wang, Swee Hin Teoh

    Research output: Contribution to journalArticle

    Abstract

    STUDY DESIGN. Algorithm development for the automatic finite element modeling of patient vertebra. OBJECTIVE. To present a technique for automatic generation of patient specific computational fluid dynamics (CFD) models for intraosseous PMMA cement flow simulation. The secondary objective is to demonstrate the possibility of using resultant PMMA cement distribution for post-PVP stress-strain analyses. SUMMARY OF BACKGROUND DATA. There are no noninvasive methods for the visualization of PMMA cement flow. In addition, optimum volume and distribution of PMMA cement are still not known. Computational models that allow patient specific intraosseous PMMA cement flow visualization as well as postvertebroplasty mechanical evaluation would be advantageous. METHODS. We developed an algorithm coded into a custom platform that inputs patient CT datasets. Hounsfield unit values were used to assign permeability values as well as modulus to the finite element model before analyses. Several user inputs are required, and these reflect the decisions made by physicians that practice vertebroplasty. As a case study, we isolated a single L1 vertebra from patient CT dataset and used our platform for model generation. Simulated vertebroplasty was performed for different PMMA cement volumes and at different placements to study the effects of varying distribution. RESULTS. Increased needle injection pressure was observed as the volume of PMMA increases and as the distribution of PMMA is in close proximity to the cortical walls. Stiffness of augmented vertebral body also increases with increased volume of PMMA administered. Varying distributions, for the same volume, of PMMA cement did not alter stiffness drastically. CONCLUSION. Our custom platform and technique for modeling vertebral bodies may contribute significantly to the science of vertebroplasty. Intraosseous PMMA cement flow can be visualized before vertebroplasty, and needle position altered for optimization. Also, parametric computational studies on the postvertebroplasty biomechanical effects of vertebroplasty are now enhanced with such a modeling capability.

    Original languageEnglish (US)
    Pages (from-to)1320-1328
    Number of pages9
    JournalSpine
    Volume32
    Issue number12
    DOIs
    StatePublished - May 1 2007

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    Vertebroplasty
    Polymethyl Methacrylate
    Hydrodynamics
    Mechanics
    Biomechanical Phenomena
    Needles
    Spine
    Permeability

    Keywords

    • Biomechanics
    • Finite element modeling
    • Vertebroplasty

    ASJC Scopus subject areas

    • Physiology
    • Clinical Neurology
    • Orthopedics and Sports Medicine

    Cite this

    Preliminary study on biomechanics of vertebroplasty : A computational fluid dynamics and solid mechanics combined approach. / Teo, Jeremy; Wang, Shih Chang; Teoh, Swee Hin.

    In: Spine, Vol. 32, No. 12, 01.05.2007, p. 1320-1328.

    Research output: Contribution to journalArticle

    Teo, Jeremy ; Wang, Shih Chang ; Teoh, Swee Hin. / Preliminary study on biomechanics of vertebroplasty : A computational fluid dynamics and solid mechanics combined approach. In: Spine. 2007 ; Vol. 32, No. 12. pp. 1320-1328.
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    abstract = "STUDY DESIGN. Algorithm development for the automatic finite element modeling of patient vertebra. OBJECTIVE. To present a technique for automatic generation of patient specific computational fluid dynamics (CFD) models for intraosseous PMMA cement flow simulation. The secondary objective is to demonstrate the possibility of using resultant PMMA cement distribution for post-PVP stress-strain analyses. SUMMARY OF BACKGROUND DATA. There are no noninvasive methods for the visualization of PMMA cement flow. In addition, optimum volume and distribution of PMMA cement are still not known. Computational models that allow patient specific intraosseous PMMA cement flow visualization as well as postvertebroplasty mechanical evaluation would be advantageous. METHODS. We developed an algorithm coded into a custom platform that inputs patient CT datasets. Hounsfield unit values were used to assign permeability values as well as modulus to the finite element model before analyses. Several user inputs are required, and these reflect the decisions made by physicians that practice vertebroplasty. As a case study, we isolated a single L1 vertebra from patient CT dataset and used our platform for model generation. Simulated vertebroplasty was performed for different PMMA cement volumes and at different placements to study the effects of varying distribution. RESULTS. Increased needle injection pressure was observed as the volume of PMMA increases and as the distribution of PMMA is in close proximity to the cortical walls. Stiffness of augmented vertebral body also increases with increased volume of PMMA administered. Varying distributions, for the same volume, of PMMA cement did not alter stiffness drastically. CONCLUSION. Our custom platform and technique for modeling vertebral bodies may contribute significantly to the science of vertebroplasty. Intraosseous PMMA cement flow can be visualized before vertebroplasty, and needle position altered for optimization. Also, parametric computational studies on the postvertebroplasty biomechanical effects of vertebroplasty are now enhanced with such a modeling capability.",
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