Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy

Christine Miaskowski, Steven M. Paul, Bruce A. Cooper, Kathryn Lee, Marylin Dodd, Claudia West, Bradley E. Aouizerat, Laura Dunn, Patrick S. Swift, William Wara

Research output: Contribution to journalArticle

Abstract

Study Objectives: To examine how self-reported ratings of sleep disturbance changed from the time of the simulation visit to four months after the completion of radiation therapy (RT) and to investigate whether specific patient, disease, and symptom characteristics predicted the initial levels of sleep disturbance and/or characteristics of the trajectories of sleep disturbance. Design: Prospective longitudinal study. Setting: Two radiation therapy centers. Patients: Patients (n = 82) who underwent primary or adjuvant RT for prostate cancer. Measurements and Results: Changes in self-reported sleep disturbance were measured using the General Sleep Disturbance Scale (GSDS). Depressive symptoms were assessed using the Center for Epidemiologic Studies-Depression Scale. Trait and state anxiety were measured using the Spielberger State-Trait Anxiety Inventory. Hierarchical linear modeling was used to answer the study aims. Self-reported sleep disturbance increased during the course of RT and then decreased following the completion of RT. Predictors of higher levels of sleep disturbance included younger age, higher levels of trait anxiety, higher levels of depressive symptoms, and higher levels of sleep disturbance at the initiation of RT. Conclusions: Sleep disturbance is a significant problem in patients with prostate cancer who undergo RT. Younger men with co-occurring depression and anxiety may be at greatest risk for sleep disturbance during RT.

Original languageEnglish (US)
Pages (from-to)171-179
Number of pages9
JournalSleep
Volume34
Issue number2
StatePublished - Feb 1 2011

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Prostatic Neoplasms
Sleep
Radiotherapy
Anxiety
Depression
Longitudinal Studies
Epidemiologic Studies
Prospective Studies
Equipment and Supplies

Keywords

  • Hierarchical linear modeling
  • Insomnia
  • Prostate cancer
  • Radiation therapy
  • Sleep disturbance
  • Symptom trajectories

ASJC Scopus subject areas

  • Physiology (medical)
  • Clinical Neurology

Cite this

Miaskowski, C., Paul, S. M., Cooper, B. A., Lee, K., Dodd, M., West, C., ... Wara, W. (2011). Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy. Sleep, 34(2), 171-179.

Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy. / Miaskowski, Christine; Paul, Steven M.; Cooper, Bruce A.; Lee, Kathryn; Dodd, Marylin; West, Claudia; Aouizerat, Bradley E.; Dunn, Laura; Swift, Patrick S.; Wara, William.

In: Sleep, Vol. 34, No. 2, 01.02.2011, p. 171-179.

Research output: Contribution to journalArticle

Miaskowski, C, Paul, SM, Cooper, BA, Lee, K, Dodd, M, West, C, Aouizerat, BE, Dunn, L, Swift, PS & Wara, W 2011, 'Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy', Sleep, vol. 34, no. 2, pp. 171-179.
Miaskowski C, Paul SM, Cooper BA, Lee K, Dodd M, West C et al. Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy. Sleep. 2011 Feb 1;34(2):171-179.
Miaskowski, Christine ; Paul, Steven M. ; Cooper, Bruce A. ; Lee, Kathryn ; Dodd, Marylin ; West, Claudia ; Aouizerat, Bradley E. ; Dunn, Laura ; Swift, Patrick S. ; Wara, William. / Predictors of the trajectories of self-reported sleep disturbance in men with prostate cancer during and following radiation therapy. In: Sleep. 2011 ; Vol. 34, No. 2. pp. 171-179.
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